NCT06151717Completed
A Comparative Clinical Study to Determine the Optimal Initial Therapy for Multiple Myeloma
PRAGMMATIC: A Comparative Clinical Trial to Determine the BEST Initial Therapy for Multiple Myeloma
Source: ClinicalTrials.gov · Last updated 17 Jun 2025
Brief summary (registry, in English)
This study evaluates the outcomes of patients undergoing initial therapy for multiple myeloma.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 50 (actual)
- First submitted
- 22 Nov 2023
- Start date
- 21 Sept 2023
- Primary completion date
- 5 Jun 2025
- Lead sponsor
- Mayo Clinic
- Diseases
- Multiple myeloma, Childhood cancers
- NCT number
- NCT06151717
What you commit to
- Study type: Observational
- Participants enrolled: 50
- From 21 Sept 2023 to the primary completion date, 5 Jun 2025
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Does not meet all inclusion criteria
Who the study is looking for
- Previously untreated active multiple myeloma starting a new treatment for the disease with one of the three established treatment regimens: VRd (bortezomib, lenalidomide, dexamethasone), DRd (daratumumab lenalidomide dexamethasone), or DVRd (daratumumab, bortezomib, lenalidomide, and dexamethasone)
- No prior treatment for myeloma
- Not receiving concurrent treatment for another active malignancy
- No more than 3 months from start of treatment
Sex: All · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mayo Clinic in Florida Coordinator of this site? Confirm its status | Jacksonville | United States | Unknown status |
| Mayo Clinic Health System-Franciscan Healthcare Coordinator of this site? Confirm its status | La Crosse | United States | Unknown status |
| Mayo Clinic in Rochester Coordinator of this site? Confirm its status | Rochester | United States | Unknown status |
| Mayo Clinic in Arizona Coordinator of this site? Confirm its status | Scottsdale | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.