NCT06152614Recruiting
MIND Foods and Aerobic Training in Black Adults With HTN
MIND Foods and Aerobic Training in Black Adults With HTN: An ADRD Prevention Pilot RCT
Source: ClinicalTrials.gov · Last updated 22 Jul 2026
Brief summary (registry, in English)
The goal of this randomized controlled trial is to determine the impact of Mediterranean-Dash Intervention for Neurodegenerative Delay (MIND) diet and aerobic training on cognition in Black adults with high systolic blood pressure. Researchers will compare Food Delivery and Cooking PLUS Aerobic Training (FoRKS+) versus Enhanced Usual Care (EUC) to evaluate the effects on cognition. Participants will complete cognitive and cardiovascular assessments, 24-hr blood pressure monitoring, standard blood pressure measurements, weight, fingerstick for HbA1c point-of-care testing, and questionnaires. Participants may also choose to participate in an optional blood draw for DNA Repair Capacity testing as a modifiable risk factor for aging-associated diseases.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 128 (estimated)
- First submitted
- 2 Nov 2023
- Start date
- 28 Nov 2023
- Primary completion date
- 31 May 2028
- Lead sponsor
- Indiana University
- Diseases
- High blood pressure
- NCT number
- NCT06152614
What you commit to
- Study type: Interventional
- Planned participants: 128
- From 28 Nov 2023 to the primary completion date, 31 May 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- drug use/abuse (excluding marijuana) per EMR
Other illness
- diagnosis of dementia or Alzheimer disease or mild cognitive impairment; Parkinson disease; brain tumor/infection/surgery (within the last 10 years with residual symptoms and/or functional loss/deficit, such as impaired learning, memory, or communication); cancer with short life expectancy, or current chemotherapy or radiation therapy; psychosis, schizophrenia, or bipolar disorder
- ICD 10 code I11/hypertensive heart disease, ICD 10 code I12/hypertensive CKD, ICD 10 code I13/hypertensive heart disease and CKD, ICD 10 code I15, or ICD 10 code I16
- low communicative ability, functional status, or other disorders (examiner rated) that would interfere with interventions and assessments
Other
- lives in nursing home
- current or past prescription of donepezil, memantine, rivastigmine, or galantamine
- alcohol consumption ≥ 8 drinks per week for women, or ≥15 drinks per week for men
- moving out of area during study timeline
- scheduling conflicts with intervention schedule
- unwilling to use a touchscreen
- unwilling to be on video conferencing
- unable to provide informed consent
- participation in any lifestyle modification/weight loss program (e.g., Weight Watchers, etc.)
Who the study is looking for
- Fluent in English
- Marion County resident
- 35-75 years
- Self-identified non-Hispanic and Black/African-American/biracial including African-American
- Systolic BP of ≥140 in prior 12 months from a primary care visit
- Ability to see and read street signs (self report)
- Stable housing with independent access to kitchen, including functional stove or hotplate, oven, refrigerator, and freezer (self report)
- Activity independence per functional activities questionnaire (FAQ; \<3 responses of "Require Assistance" and 0 responses of "Dependent")
- Normal cognition per six-item screener (SIS; score of ≥ 5)
- Less than 20min on usual day of moderate or vigorous physical activity
- Able to exercise safely per abbreviated Exercise Assessment for You (EASY) or primary care provider clearance
- Mean systolic BP of ≥130 from 3 standard BP measurements taken by research staff following standardized wait periods.
Age in the registry: 35 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Eskenazi Health Coordinator of this site? Confirm its status | Indianapolis | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.