NCT06155786Completed
Cognitive Effects of tDCS and tRNS in Schizophrenia
Cognitive Effects of Transcranial Direct Current Stimulation (tDCS) and Transcranial Random Noise Stimulation (tRNS) in Schizophrenia: A Random, Crossover Study
Source: ClinicalTrials.gov · Last updated 18 Mar 2026
Brief summary (registry, in English)
The purpose of this study is to investigate the cognitive effects of different electrical stimulation modalities, such as transcranial direct and random-noise stimulation over the dorsolateral prefrontal cortex, in schizophrenia.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 36 (actual)
- First submitted
- 24 Nov 2023
- Start date
- 1 Jan 2023
- Primary completion date
- 1 Nov 2023
- Lead sponsor
- The National Brain Mapping Laboratory (NBML)
- Diseases
- Schizophrenia
- NCT number
- NCT06155786
What you commit to
- Study type: Interventional
- Participants enrolled: 36
- From 1 Jan 2023 to the primary completion date, 1 Nov 2023
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Presence of ferromagnetic objects in the body that are contraindicated for brain stimulation of the head (pacemakers or other implanted electrical devices, brain stimulators, some types of dental implants, aneurysm clips, metallic prostheses, permanent eyeliner, implanted delivery pump, or shrapnel fragments)
Other illness
- comorbid bipolar disorder and mood disorder
- history of seizure
- history of neurological disorder
- history of head injury
Other
- pregnancy
- alcohol or substance dependence
Who the study is looking for
- Diagnosis of schizophrenia based on Diagnostic and Statistical Manual (DSM)5
- Being 18-50 years old (male and female)
- If female, negative urine pregnancy test
- feasibility for tDCS/tRNS interventions according to safety guidelines
- stable medication regime, especially for classical neuroleptics and all central nervous system activating medications, if taken, 4-6 weeks before the experiment
- fluency in the native language
- right-handed
- Required written informed consent signed by patients' guardian
Age in the registry: 18 years to 50 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Payame Noor University, Tehran Branch Coordinator of this site? Confirm its status | Tehran | Iran | Unknown status |
| Zanjan University Coordinator of this site? Confirm its status | Zanjān | Iran | Unknown status |
Related publications
- Cognitive and emotional effects of bilateral prefrontal anodal tDCS and high-frequency tRNS in schizophrenia: a randomized sham-controlled study.Schizophrenia (Heidelb) · 2026 · PMID 41530140
This page is information, not medical advice. Discuss any trial with your doctor.