NCT06156202Completed
Evaluating a Comprehensive Multimodal Outpatient Rehabilitation Program for PASC Program to Improve Functioning of Persons Suffering From Post-COVID-19 Syndrome: A Randomized Controlled Trial
Evaluating a Comprehensive Multimodal Outpatient Rehabilitation Program to Improve the Functioning of Persons Suffering From Post-acute Sequelae of SARS-CoV-2 Infection (PASC): A Randomized Controlled
Source: ClinicalTrials.gov · Last updated 20 Jan 2026
Brief summary (registry, in English)
About 10-20% of persons who contract SARS CoV-2 will experience persistent post-acute sequelae of SARSCoV-2 infection (referred here as PASC). While treatments offered at emerging outpatient COVID recovery clinics are being informed by previous similar diseases, the need is great for a better understanding of the unique needs of this growing population and for tested, efficacious rehabilitation programs to address them. We provide both here.The targeted six-week program will be comprised of a core set of therapies, including individually titrated stretching and flexibility, strengthening of accessory breathing muscles and diaphragm, resistance and aerobic conditioning, and vestibular rehabilitation, supplemented by neuropsychological and cognitive remediation tailored to patients' needs.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 125 (actual)
- First submitted
- 28 Nov 2023
- Start date
- 15 Nov 2023
- Primary completion date
- 30 Nov 2025
- Lead sponsor
- University of Pennsylvania
- Diseases
- Long COVID and ME/CFS
- NCT number
- NCT06156202
What you commit to
- Study type: Interventional
- Participants enrolled: 125
- From 15 Nov 2023 to the primary completion date, 30 Nov 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Severe cognitive impairment (i.e. Alzheimer's, Dementia)
Other
- Participation in another clinical trial
- Score greater than 12 on the fatigue scale
- Score greater than 30 on the memory/thinking scale
- Mental or physical inability to participate in the program
Who the study is looking for
- 18 years if age or older
- English or Spanish speaking
- Previously tested positive for COVID
- Still having symptoms not explained by any other etiologies
- Cognitive impairment
- Fatigue
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital of the University of Pennsylvania Coordinator of this site? Confirm its status | Philadelphia | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.