NCT06158581Recruiting
Comparing Two Different Emotion Therapies for Autistic Youth and Young Adults
The Emotion Awareness and Skills Enhancement (EASE) Program Versus the Unified Protocol (UP)
Source: ClinicalTrials.gov · Last updated 13 Apr 2026
Brief summary (registry, in English)
Too few clinicians are able and willing to help autistic patients. A recent review identified challenges to mental health service delivery in autism, including a lack of interventions designed for community implementation and limited workforce capacity. It has been argued that improving impairment in emotion regulation has the potential to improve a range of mental health difficulties in autistic people. In this clinical trial, the investigators are comparing two evidence-based interventions for emotion regulation, to determine if one created specifically for autistic people is clinically superior. The interventions will be implemented in the community, through partnering agencies.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 470 (estimated)
- First submitted
- 27 Nov 2023
- Start date
- 8 Apr 2024
- Primary completion date
- 1 Aug 2027
- Lead sponsor
- University of Pittsburgh
- Diseases
- Autism
- NCT number
- NCT06158581
What you commit to
- Study type: Interventional
- Planned participants: 470
- From 8 Apr 2024 to the primary completion date, 1 Aug 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- \- Higher level of care is needed (Imminent Suicide / Homicide Threat, acute psychosis, mania)
Who the study is looking for
- professional diagnosis of ASD
- a score in the clinical range on the EDI-Reactivity or EDI-Dysphoria scale based on caregiver report or self-report
- The study is open to people with a range of communication abilities. Participants must be able to consent to the study themselves and answer questions about themselves.
- Participants need to have a support person that could answer questions about them too. This could be a parent, caregiver, family member, partner or friend. Independent adults can opt out of this portion.
- Participants must live in Alabama or Pennsylvania.
Age in the registry: 10 years to 30 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Pittsburgh Coordinator of this site? Confirm its status | Pittsburgh | United States | Recruiting |
| University of Alabama Coordinator of this site? Confirm its status | Tuscaloosa | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.