NCT06159595Completed
Behavioral and Neuronal Correlates of Human Mood States
Source: ClinicalTrials.gov · Last updated 2 Nov 2026
Brief summary (registry, in English)
Optimizing treatments in mental health requires an easy to obtain, continuous, and objective measure of internal mood. Unfortunately, current standard-of-care clinical scales are sparsely sampled, subject to recency bias, underutilized, and are not validated for acute mood monitoring. The recent shift to remote care also requires novel methods to measure internal mood. Recent advances in computer vision have allowed the accurate quantification of observable speech patterns and facial representations. The continuous and objective nature of these audio-facial behavioral outputs also enable the study of their neural correlates. Here, the investigators hypothesize that video-derived audio-facial behaviors have discrete neural representations in the limbic network and can provide a critical set of reliable longitudinal estimates of mood at low cost across home and clinic settings.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 11 (actual)
- First submitted
- 16 Nov 2023
- Start date
- 1 Dec 2023
- Primary completion date
- 7 Nov 2025
- Lead sponsor
- Stanford University
- Diseases
- Epilepsy, Depression
- NCT number
- NCT06159595
What you commit to
- Study type: Observational
- Participants enrolled: 11
- From 1 Dec 2023 to the primary completion date, 7 Nov 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Diffuse epilepsy involving several lobes of the brain
Who the study is looking for
- Age range between 18 and 65
- Major depressive disorder (MDD) in a current major depressive episode diagnosed with the Mini-International Neuropsychiatric Interview (MINI)
- No medical or surgical contraindication to electrode implantation
- Patient capable of understanding the scope of our project or signing informed consent independently.
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Stanford University Coordinator of this site? Confirm its status | Stanford | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.