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NCT06159595Completed

Behavioral and Neuronal Correlates of Human Mood States

Source: ClinicalTrials.gov · Last updated 2 Nov 2026

Brief summary (registry, in English)

Optimizing treatments in mental health requires an easy to obtain, continuous, and objective measure of internal mood. Unfortunately, current standard-of-care clinical scales are sparsely sampled, subject to recency bias, underutilized, and are not validated for acute mood monitoring. The recent shift to remote care also requires novel methods to measure internal mood. Recent advances in computer vision have allowed the accurate quantification of observable speech patterns and facial representations. The continuous and objective nature of these audio-facial behavioral outputs also enable the study of their neural correlates. Here, the investigators hypothesize that video-derived audio-facial behaviors have discrete neural representations in the limbic network and can provide a critical set of reliable longitudinal estimates of mood at low cost across home and clinic settings.

Status (registry)
Completed
Study type
Observational
Enrollment
11 (actual)
First submitted
16 Nov 2023
Start date
1 Dec 2023
Primary completion date
7 Nov 2025
Lead sponsor
Stanford University
NCT number
NCT06159595

What you commit to

  • Study type: Observational
  • Participants enrolled: 11
  • From 1 Dec 2023 to the primary completion date, 7 Nov 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Diffuse epilepsy involving several lobes of the brain

Who the study is looking for

  • Age range between 18 and 65
  • Major depressive disorder (MDD) in a current major depressive episode diagnosed with the Mini-International Neuropsychiatric Interview (MINI)
  • No medical or surgical contraindication to electrode implantation
  • Patient capable of understanding the scope of our project or signing informed consent independently.

Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Stanford University
Coordinator of this site? Confirm its status
StanfordUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.