NCT06160076Completed
Inflammatory Response Following " Pulsed Field Ablation " vs. Radiofrequency Ablation-2
Inflammatory Response Following " Pulsed Field Ablation " vs. Radiofrequency Ablation of Paroxysmal Atrial Fibrillation-2
Source: ClinicalTrials.gov · Last updated 17 Jun 2025
Brief summary (registry, in English)
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. Catheter ablation using pulmonary vein isolation (PVI) in an established treatment strategy for AF. Pulsed Field Ablation (PFA) is a non-thermal ablation modality which has recently been introduced in clinical practice with the aim of improving PVI efficacy and safety. The aim of this study is to analyse whether PFA generates a lower inflammatory reaction as compared to conventional radiofrequency ablation (RFA).
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 63 (actual)
- First submitted
- 28 Sept 2023
- Start date
- 16 Oct 2023
- Primary completion date
- 11 Oct 2024
- Lead sponsor
- University Hospital, Bordeaux
- Diseases
- Atrial fibrillation
- NCT number
- NCT06160076
What you commit to
- Study type: Observational
- Participants enrolled: 63
- From 16 Oct 2023 to the primary completion date, 11 Oct 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior left atrial ablation
- Prior cardiac surgery comprising incision of the left atrium
- Prior myocardial infarction or stroke in the previous 30 days
- Antiplatelet therapy (e.g. aspirine, clopidogrel) within the 7 last days
- Anti-inflammatory treatment (e.g. glucocorticoids, colchicine, cyclophosphamide, azathioprine, mycophenolic acid, antibodies) within the 7 last days
Other illness
- Acute or chronic inflammatory state: active smoking, auto-immune disease, active tumor disease, myocarditis
Age
- Age \< 18 years
Other
- Persons under judicial protection (guardianship, guardianship) or deprived of freedom
Who the study is looking for
- Age ≥ 18 years
- Patients with paroxysmal AF referred for first-time catheter ablation using PFA or RFA
- Non-opposition to participate
Age in the registry: 18 years to 100 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hopital Haut-Leveque Coordinator of this site? Confirm its status | Pessac | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.