Time-restricted Enteral Nutrition Versus Continuous Enteral Nutrition in Patients With Severe Stroke

Prior treatment

• After gastrectomy or intestinal resection;

Other illness

• Have a history of mental illness or mRS ≥ 3 points;
• During the patient's admission, death is inevitable, and there are underlying diseases that result in a survival time of \<90 days;

Lab values

• Accompanying diseases: a. Advanced cancer; b. Severe cardiac insufficiency \[ejection fraction ≤ 50%\]; c. Severe liver failure \[Child Pugh score ≥ 7\]; d. Severe renal failure \[glomerular filtration\] rate ≤ 30 mL/min or serum creatinine ≥ 4 mg/dL\])

Other

• Complete parenteral nutrition is required due to contraindications to enteral nutrition;
• Enteral nutrition treatment has been performed for \>12 hours;
• The patient's doctor or nutritional therapist believes that the plan is not in the best interest of the patient;
• The patient participates in another clinical study.

• Age ≥18 years old and \<80 years old;
• Cerebral parenchymal hemorrhage or cerebral infarction within 72 hours of onset;
• GCS score ≤12 points or NIHSS score ≥11 points on admission,
• Enteral nutrition is planned, and the estimated enteral nutrition treatment time is ≥7 days;
• Signed informed consent form.