NCT06164795Recruiting
Sequential Therapies After Osteoanabolic Treatment
Efficacy of Sequential Therapies After Osteoanabolic Treatment in Postmenopausal Women With Severe Osteoporosis: the Sequential Treatment After Romosozumab and Teriparatide/Abaloparatide (START) Study
Source: ClinicalTrials.gov · Last updated 22 Jul 2026
Brief summary (registry, in English)
12-month prospective, open-label, multicenter, international, observational study evaluating sequential treatments after osteoanabolics
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 150 (estimated)
- First submitted
- 29 Nov 2023
- Start date
- 25 Nov 2023
- Primary completion date
- 1 Jun 2027
- Lead sponsor
- 424 General Military Hospital
- Diseases
- Osteoporosis
- NCT number
- NCT06164795
What you commit to
- Study type: Observational
- Planned participants: 150
- From 25 Nov 2023 to the primary completion date, 1 Jun 2027
- 8 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- use of medications other than romosozumab or teriparatide affecting bone metabolism during the last 12 months before entering the study
Other illness
- a bone disease other than postmenopausal osteoporosis
- liver failure
- any type of cancer
- uncontrolled endocrine diseases
- hypersensitivity to denosumab or zoledronate or teriparatide or romosozumab or any of the excipients
Lab values
- creatinine clearance \<60 mL/min/1.73 m2
- serum 25-hydroxy vitamin D (25-OHD) concentrations lower than 20 ng/mL (50 nmol/L)
Who the study is looking for
- Postmenopausal women treated with severe osteoporosis completing their course with romosozumab or teriparatide
Age in the registry: 50 years to 85 years · Sex: Female · Does not accept healthy volunteers
Sites (8)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| 251 Airforce & VA General Hospital Coordinator of this site? Confirm its status | Athens | Greece | Recruiting |
| KAT General Hospital Coordinator of this site? Confirm its status | Athens | Greece | Recruiting |
| First Department of Propaedeutic and Internal Medicine, Medical School, National and Kapodistrian University of Athens Coordinator of this site? Confirm its status | Athens | Greece | Recruiting |
| 424 General Military Hospital Coordinator of this site? Confirm its status | Thessaloniki | Greece | Recruiting |
| Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico Coordinator of this site? Confirm its status | Milan | Italy | Recruiting |
| Campus Bio-Medico University Coordinator of this site? Confirm its status | Roma | Italy | Recruiting |
| Department of Medicine, Surgery and Neurosciences, University of Siena Coordinator of this site? Confirm its status | Siena | Italy | Recruiting |
| University-Hospital S. Maria della Misericordia Coordinator of this site? Confirm its status | Udine | Italy | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.