NCT06165510Recruiting
Convergent Ablation Plus Left Atrial Appendage Isolation for the Treatment of Persistent Atrial Fibrillation
Source: ClinicalTrials.gov · Last updated 25 Jun 2026
Brief summary (registry, in English)
A randomised controlled clinical trial to assess efficacy of convergent ablation with the LARIAT procedure, as compared to standard endocardial catheter ablation in patients with long-standing persistent atrial fibrillation (AF).
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 48 (estimated)
- First submitted
- 15 Aug 2023
- Start date
- 2 Aug 2024
- Primary completion date
- 1 Nov 2026
- Lead sponsor
- Barts & The London NHS Trust
- Diseases
- Atrial fibrillation
- NCT number
- NCT06165510
What you commit to
- Study type: Interventional
- Planned participants: 48
- From 2 Aug 2024 to the primary completion date, 1 Nov 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Subject is absent of LAA or if the LAA is previously surgically ligated
- Subject has had previous cardiac surgery or abdominal surgery.
- Subject has had previous catheter or surgical ablation
Other illness
- Patients with significant valve disease.
Other
- Subjects currently enrolled in another investigational study except in case of observational registry with no associated treatments.
- Subject has a reversible cause of AF or transient AF
- Subject has contraindication to anticoagulation.
- Patients with hypertrophic cardiomyopathy.
Who the study is looking for
- Age \> 18 years; \< 80 years
- Persistent AF \> 1-year duration
- Left atrium size \< 6cm
- Pts should be able to provide written informed consent.
Age in the registry: 18 years to 80 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| St. Bartholomew's Hospital Coordinator of this site? Confirm its status | London | United Kingdom | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.