NCT06166095Completed
Dose-Response Effect Exercise and Depression
Dose-Response Effect of Exercise on Depression and Brain-Derived Neurotrophic Factor (BDNF) in Sedentary Young Adults
Source: ClinicalTrials.gov · Last updated 27 Mar 2025
Brief summary (registry, in English)
The present study aims to address gaps in the literature by evaluating the objectively measured dose-response relationship between exercise and depression symptoms; examining changes in resting (Brain-derived Neurotrophic Factor) BDNF from baseline to week 10 of an exercise intervention; and assessing varying exercise intensities on enjoyment, affect, and health-related quality of life in sedentary young adult college students.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 48 (actual)
- First submitted
- 28 Sept 2023
- Start date
- 1 Jul 2023
- Primary completion date
- 1 Dec 2024
- Lead sponsor
- University of Central Florida
- Diseases
- Depression
- NCT number
- NCT06166095
What you commit to
- Study type: Interventional
- Participants enrolled: 48
- From 1 Jul 2023 to the primary completion date, 1 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- current cognitive therapy or antidepressant medication
- beta-blocker medications
Other illness
- history of bad reaction to a past blood draw
- diagnosis of a co-occurring condition such as attention deficit hyperactivity disorder (ADHD)
- diagnosis of a serious mental illness (SMI) such as schizophrenia or bipolar disorder
Other
- under 110 lbs
- have been advised by a medical provider to not give/donate blood
- presence of anemia
- pregnant or nursing
- current smoker
Who the study is looking for
- enrolled UCF college students aged 18 to 25
- mild to moderate depressive symptoms
- willing to wear a Fitbit for extended periods of time during the study
- willing to participate in moderate-to-vigorous PA
- physically able to participate in exercise safely
Age in the registry: 18 years to 25 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Central Florida Coordinator of this site? Confirm its status | Orlando | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.