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NCT06166303Not yet recruiting

Number of Previous Cesarean Sections on the Results of Angiogenic Factors.

Effect of Number of Previous Cesarean Sections on the Results of Angiogenic Factors. A Descriptive, Prospective Study.

Source: ClinicalTrials.gov · Last updated 26 Aug 2025 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

Hypertensive disorders of pregnancy (HPT) are an important cause of maternal-feto-neonatal morbidity and mortality, being one of the three leading causes of maternal death in our country and in developing countries. The only cure for THE is termination of pregnancy, which ends up being a decision in which gestational age and maternal risks must be balanced. Angiogenic factors have come to occupy an indispensable place in the arsenal of tools that can be used to separate the patient with a high likelihood of complications from those in whom prolongation of pregnancy could represent an important neonatal benefit. Although the usefulness of angiogenic factors in these scenarios is known, little is known about the effects that other conditions might have on their serum levels, mainly those that have an effect on trophoblastic invasion, the process that initiates implantation of the pregnancy in the endometrium. The purpose of the present study is to assess the effect that a history of uterine surgery, such as caesarean section, might have on angiogenic factor scores in subjects with no history of a hypertensive disorder of pregnancy.

Status (registry)
Not yet recruiting
Study type
Observational
Enrollment
540 (estimated)
First submitted
4 Dec 2023
Start date
1 Oct 2025
Primary completion date
30 Jan 2026
Lead sponsor
Saint Thomas Hospital, Panama
NCT number
NCT06166303

What you commit to

  • Study type: Observational
  • Planned participants: 540
  • From 1 Oct 2025 to the primary completion date, 30 Jan 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Renal failure
  • Liver disease

Other

  • Vasculitis
  • Twin pregnancy
  • Chronic endometritis
  • Smoking
  • Lupus
  • Thrombocytopenia

Who the study is looking for

  • 36 weeks of gestation or more
  • Singleton pregnancy
  • Previous cesarean section (case)

Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Saint Thomas H
Coordinator of this site? Confirm its status
Panama CityPanamaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.