NCT06166706Recruiting
Current Practice of Ventilation Strategies in Children Undergoing General Anesthesia
Current Practice of Ventilation Strategies in Children Undergoing General Anesthesia and Associations With Postoperative Pulmonary Complications - a Multicenter Prospective Cohort Study
Source: ClinicalTrials.gov · Last updated 9 Apr 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Postoperative pulmonary complications (PPCs) are common in children undergoing general anesthesia and are associated with prolonged stay in the hospital and high costs. Development of PPCs is associated with ventilator settings in adult patients undergoing general anesthesia. Data on perioperative ventilator settings in children are lacking, leaving the anaesthetist without guidance. Consequently, the current standard of care in perioperative mechanical ventilation in children is expected to be extremely heterogeneous, leading to ventilation with higher levels of energy than necessary. Therefore, it is highly necessary to evaluate the current practice in perioperative ventilation in children and to determine associations with PPCs.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 10000 (estimated)
- First submitted
- 4 Dec 2023
- Start date
- 29 Jan 2024
- Primary completion date
- 30 Dec 2025
- Lead sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
- NCT number
- NCT06166706
What you commit to
- Study type: Observational
- Planned participants: 10000
- From 29 Jan 2024 to the primary completion date, 30 Dec 2025
- 4 sites in 4 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- patients undergoing surgical procedures involving extra-corporal circulation;
- patients receiving ventilation with high frequency jet ventilation or high frequency oscillatory ventilation;
Other
- sedation without airway management in the form of a endotracheal tube or a supraglottic airway device; and
- (rigid) bronchoscopic procedures with maintenance of spontaneous ventilation.
Who the study is looking for
- aged ≤ 16 years;
- undergoing general anesthesia
- airway management with tube or LMA; and
- connected to mechanical ventilator . minimum duration of procedure: 15 minutes
Age in the registry: - to 16 years · Sex: All · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Perth Children's Hospital Coordinator of this site? Confirm its status | Perth | Australia | Not yet recruiting |
| Universitatsspital Bern Coordinator of this site? Confirm its status | Bern | Switzerland | Not yet recruiting |
| IRCCS Istituto Giannina Gaslini Coordinator of this site? Confirm its status | Genoa | Italy | Not yet recruiting |
| Amsterdam University Medical Centers Coordinator of this site? Confirm its status | Amsterdam | Netherlands | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.