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NCT06169241RecruitingEarly phase 1

Effect of Nitrate Supplementation on Blood Pressure and Microvascular Function of Resistant Hypertensive Patients

Effect of Nitrate Supplementation on Blood Pressure and Systemic Microvascular Function of Resistant Hypertensive Patients

Source: ClinicalTrials.gov · Last updated 13 Apr 2026

Brief summary (registry, in English)

Arterial hypertension (AH) has been identified as an important public health problem and considered a new epidemic with high mortality and morbidity. High blood pressure (BP) levels increase the chances of coronary artery disease (CAD), heart failure (HF), stroke, chronic renal failure (CRF) and death. Beetroot powder may be an easier way to increase the availability of nitric oxide and consequently vasodilation in these patients. However, studies are needed to evaluate its benefits in patients with AH.

Status (registry)
Recruiting
Phase (registry)
Early phase 1
Study type
Interventional
Enrollment
50 (estimated)
First submitted
5 Dec 2023
Start date
1 Nov 2023
Primary completion date
Dec 2026
Lead sponsor
National Institute of Cardiology, Laranjeiras, Brazil
NCT number
NCT06169241

What you commit to

  • Study type: Interventional · Early phase 1
  • Planned participants: 50
  • From 1 Nov 2023 to the primary completion date, Dec 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • use of medications with nitrate in their formula

Other illness

  • heart failure

Other

  • neoplasms
  • patients undergoing renal denervation

Who the study is looking for

  • Resistant hypertension, with a diagnosis described in the medical record, without changing medications or increasing doses in the last 30 days.

Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
National Institute of Cardiology
Coordinator of this site? Confirm its status
Rio de JaneiroBrazilRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.