NCT06171945Completed
Mobile Weight Loss Intervention for Adolescent and Young Adult Cancer Survivors
A Pilot Randomized Trial of a Mobile Weight Loss Intervention for Adolescent and Young Adult Cancer Survivors
Source: ClinicalTrials.gov · Last updated 27 Oct 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The purpose of this study is to conduct a 6-month pilot randomized trial to determine the feasibility and acceptability of theory-based mobile weight loss interventions for survivors of adolescent and young adult cancer (AYAs). The interventions use a mobile smartphone application, previously developed for individuals at risk for type 2 diabetes and adapted for AYAs, that integrates weight and physical activity from digital devices with simplified dietary monitoring in a behavioral weight loss program.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 63 (actual)
- First submitted
- 27 Nov 2023
- Start date
- 1 Mar 2024
- Primary completion date
- 13 Jul 2025
- Lead sponsor
- UNC Lineberger Comprehensive Cancer Center
- Diseases
- Head and neck cancer, Thyroid cancer, Obesity, Kidney cancer, Bladder cancer, Melanoma, Endometrial cancer, Cervical cancer, Pancreatic cancer, Colorectal cancer, Liver and biliary tract cancer, Sarcoma
- NCT number
- NCT06171945
What you commit to
- Study type: Interventional
- Participants enrolled: 63
- From 1 Mar 2024 to the primary completion date, 13 Jul 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Type 1 diabetes or currently receiving medical treatment for Type 2 diabetes
- Report a history of heart attack or stroke within the previous 6 months
- Past diagnosis of or receiving treatment for a clinically diagnosed eating disorder (anorexia nervosa or bulimia nervosa) or any compensatory behaviors within the previous 3 months
- Currently using prescription medications with known effects on appetite or weight.
- Previous surgical procedure for weight loss or planned weight loss surgery in the next 6 months
Other illness
- Untreated thyroid disease or any changes (type or dose) in thyroid medication in the last 6 months
- Hospitalization for depression or other psychiatric disorder within the past 12 months
- History of psychotic disorder or bipolar disorder
Other
- Health problems that preclude the ability to walk for physical activity
- Lost 5% or more of body weight (and kept it off) in the last 3 months
- Currently pregnant, pregnant within the past 6 months, or planning to become pregnant within the next 6 months
- Currently participating in a weight loss, nutrition, or physical activity study or program or other study that would interfere with this study
- Inability to speak and read English
- Do not have an iPhone with active data and text messaging plan
- No Internet access
- Not willing to be randomized to either intervention arm
Who the study is looking for
- Currently age 18-39
- Diagnosed with first invasive cancer between the ages of 15-39 years old
- Within 10 years of diagnosis with no evidence of progressive disease or second primary cancers
- Completed active cancer-directed therapy (cytotoxic chemotherapy, radiation therapy, and/or definitive surgical intervention) at least six months prior to enrollment, except maybe receiving "maintenance" therapy to prevent recurrences
- Body Mass Index (BMI) of 25-50 kg/m2
Criteria the registry did not label
- In order to participate in this study a subject must meet all of the eligibility criteria outlined below.
Age in the registry: 18 years to 39 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Lineberger Comprehensive Cancer Center at University of North Carolina, Chapel Hill Coordinator of this site? Confirm its status | Chapel Hill | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.