NCT06180837Recruiting
Effect of Sleep Extension on Ceramides in People With Overweight and Obesity
Biomarkers of Habitual Short Sleep and Related Cardiometabolic Risk
Source: ClinicalTrials.gov · Last updated 5 Aug 2026
Brief summary (registry, in English)
The overall goal is to determine how a sleep extension intervention (increasing time in bed) in individuals who maintain less than 6.5 hours sleep per night affects their plasma ceramides and insulin sensitivity. Participants will undergo a randomized controlled trial, with sleep extension (intervention) and healthy lifestyle (control) groups. The sleep extension is designed to increase participant's time in bed by 2 hours per night. Alternatively, the control group will receive basic health information (e.g., physical activity, goal setting, and nutrition when eating out).
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 70 (estimated)
- First submitted
- 14 Nov 2023
- Start date
- 12 Feb 2024
- Primary completion date
- Jan 2028
- Lead sponsor
- University of Utah
- Diseases
- Obesity, Type 2 diabetes
- NCT number
- NCT06180837
What you commit to
- Study type: Interventional
- Planned participants: 70
- From 12 Feb 2024 to the primary completion date, Jan 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Weight change: \>10% of body weight over prior six months
Other illness
- Clinically diagnosed sleep disorder or major psychiatric illness
- Evidence of significant organ dysfunction or disease (e.g., heart disease, kidney disease)
- Cancer that has been in remission less than 5 years
- Shift-work: current or history of within last year
- Current enrollment in weight loss or physical activity program like the Diabetes Prevention Program
Lab values
- Clinically diagnosed diabetes or fasting plasma glucose ≥126 mg/dL or HbA1c ≥6.5%
- Use of prescription drugs or substances known to influence sleep or glucose metabolism, or anticoagulant medications.
Other
- Pregnant/nursing, experiencing menopause or post-menopausal
- Currently smoking
- Alcohol intake\>14 drinks per week or \>3 drinks per day
Who the study is looking for
- Age: 18-45 years old; equal numbers of men and women
- Body mass index (BMI): 27.5-34.9 kg/m2
- Sleep Habits: habitual self-reported average total sleep time (TST) \<6.5 hours per night for prior 6 months
Age in the registry: 18 years to 45 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| College of Health Research Complex--University of Utah Coordinator of this site? Confirm its status | Salt Lake City | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.