NCT06185023Completed
Effects of High-intensity Exercise Training on Physical Fitness, Cognition, Language in Post-stroke Aphasia
Exercising Language: Behavioral and Neurophysiological Changes After High-intensity Exercise Training in Post-stroke Aphasia
Source: ClinicalTrials.gov · Last updated 17 Feb 2026
Brief summary (registry, in English)
The goal of this clinical trial is to establish the feasibility and fidelity of a high-intensity exercise program for individuals with post-stroke aphasia. The main questions it aims to answer are: * Is it feasible for stroke survivors with aphasia to participate in a long in-person physical exercise program? * Does participation in a physical exercise program lead to physical fitness, cognitive, language and/or psychological changes? Participants can take part in two different physical exercise interventions: * Low intensity intervention (control intervention); * High-intensity physical exercise intervention (target intervention).
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 12 (actual)
- First submitted
- 14 Dec 2023
- Start date
- 11 Dec 2023
- Primary completion date
- 12 Sept 2025
- Lead sponsor
- University of California, Berkeley
- Diseases
- Stroke
- NCT number
- NCT06185023
What you commit to
- Study type: Interventional
- Participants enrolled: 12
- From 11 Dec 2023 to the primary completion date, 12 Sept 2025
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- prior history of dementia, neurologic illness (other than stroke), or substance abuse;
Other illness
- per self-report uncontrolled cardiorespiratory and/or metabolic disorders incompatible with exercise.
Other
- significant visual or hearing disabilities (e.g., neglect, uncorrected visual or hearing loss) that interfere with testing;
Who the study is looking for
- aphasia following single or multiple ischemic or hemorrhagic stroke;
- at least 6 months from the last stroke;
- proficient in English before the stroke;
- at least 8 years of education;
- between the ages of 18 and 80;
- independent with ambulation without a device (single-point cane accepted);
- medically stable with no contraindications to participate in regular physical exercise as determined by the patient's own primary care provider or other treating provider.
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of California, Berkeley Coordinator of this site? Confirm its status | Berkeley | United States | Unknown status |
| California State University, East Bay Coordinator of this site? Confirm its status | Hayward | United States | Unknown status |
| University of San Francisco Coordinator of this site? Confirm its status | San Francisco | United States | Unknown status |
| University of California San Francisco Coordinator of this site? Confirm its status | San Francisco | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.