NCT06189001Completed
The Role of Oxytocin-receptor Signalling in Physiological Regulation of Eating Behaviour in Individuals with Obesity
Source: ClinicalTrials.gov · Last updated 27 Mar 2025
Brief summary (registry, in English)
The present study evaluates appetite, glucose metabolism, gastrointestinal motility and energy expenditure in men and women with obesity (BMI 30-40 kg/m2) under oxytocin exposure compared to placebo.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 25 (actual)
- First submitted
- 5 Dec 2023
- Start date
- 1 Jan 2024
- Primary completion date
- 4 Sept 2024
- Lead sponsor
- University Hospital, Gentofte, Copenhagen
- Diseases
- Obesity
- NCT number
- NCT06189001
What you commit to
- Study type: Interventional
- Participants enrolled: 25
- From 1 Jan 2024 to the primary completion date, 4 Sept 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous gastric or intestinal resection, cholecystectomy and/or any major intra-abdominal surgery (including bariatric surgery)
- Previous pancreatic disease and/or neoplasia
- Initiation of special diets, lifestyle changes and/or weight loss \>5% of total body weight within three months prior to or during study period
Other illness
- History of hepatobiliary and/or gastrointestinal disorder(s)
- Pituitary gland disorders
- Any physical or psychological condition or ongoing medication the investigator group suspect would interfere with trial participation
Lab values
- Anaemia (haemoglobin below normal range)
- Alanine aminotransferase (ALT) \>2 times normal values
- Kidney disease (serum creatinine above normal range and/or urine albumin-creatinine ratio (uACR) \>30 mg/g confirmed by two measures)
- Glycated haemoglobin (HbA1c) ≥48 and/or type 1 diabetes or type 2 diabetes requiring medical treatment
- Long QTc on electrocardiogram (ECG) at screening (≥0.45 seconds for men and ≥0.46 seconds for women)
Other
- Regular tobacco smoking and/or use of other nicotine products
- Pregnancy or breastfeeding
Who the study is looking for
- Age 18-65 years
- BMI between 30 and 40 kg/m2 (both included)
- Percentage body fat (BF%) ≥25 for men and ≥32 for women (assessed by bioelectrical impedance analysis)
- Informed oral and written consent
Age in the registry: 18 years to 65 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Center for Clinical Metabolisk Research Coordinator of this site? Confirm its status | Hellerup | Denmark | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.