Real-world Experience of ICIs Plus Chemotherapy With or Without Radiotherapy for Advanced ESCC.

Prior treatment

• Those who have a history of autoimmune disease or have been treated with immunosuppressants within the last 3 months.
• Those who have received organ transplant surgery.

Other illness

• Surgery for esophageal cancer;
• Risk of gastrointestinal bleeding, oesophageal fistula or oesophageal perforation
• Patients with a previous history of malignant tumor (skin basal cell carcinoma and cervical carcinoma in situ) survived tumor-free for 3 years after treatment.
  • Except for the above).
• There are other serious diseases, such as myocardial infarction, cerebral infarction or severe cardiopulmonary insufficiency within 6 months

Other

• Esophageal fistulae due to infiltration of the primary tumour.

• Pathologically diagnosed as esophageal squamous cell carcinoma;
• The clinical stage is IVb stage, that is, non-regional lymph node metastasis and distant organ metastasis (AJCC8th) of esophageal carcinoma.
• Patients had received no previous systemic therapy
• Patients who had received at least one cycle of first-line chemotherapy combined with immunotherapy, received or did not receive radiotherapy;
• Complete medical records;
• ECOG0-2;