NCT06191380Completed
Effects of Cycling and Virtual Reality on Thinking Speed in Persons With MS (PACE-MS)
Effects of a Single Bout of Moderate Intensity Aerobic Cycling Exercise Combined With Virtual Reality on Processing Speed in Persons With Multiple Sclerosis and Mobility Disability
Source: ClinicalTrials.gov · Last updated 30 Oct 2025
Brief summary (registry, in English)
To compare the effects of cycling exercise with different types of virtual reality on processing/thinking speed in persons with multiple sclerosis (MS).
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 23 (actual)
- First submitted
- 19 Dec 2023
- Start date
- 12 Feb 2024
- Primary completion date
- 28 Oct 2025
- Lead sponsor
- Kessler Foundation
- Diseases
- Multiple sclerosis
- NCT number
- NCT06191380
What you commit to
- Study type: Interventional
- Participants enrolled: 23
- From 12 Feb 2024 to the primary completion date, 28 Oct 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Currently use medications that may impact cognition (ex: steroids, benzodiazepines)
Other illness
- History of neurological disorders besides MS or history of uncontrolled psychiatric disorders (ex: major depression)
- Severe cognitive impairment as measured by the Modified Telephone Interview of Cognitive Status (TICS-M)
Age
- No indication of age-related mild cognitive impairment or dementia, based on the MOCA-Blind (i.e., MOCA-Blind ≥19).
Other
- Have contraindications to exercise, based on the Physical Activity Readiness Questionnaire (PAR-Q)
- Currently pregnant
- High likelihood of motion sickness
- Regular cyclist, defined as cycling for at least 150 minutes/week
Who the study is looking for
- Speak English as their primary language
- Confirmed MS diagnosis by a neurologist
- Be relapse and steroid-free for at least 30 days
- Mild-to-moderate self-report mobility disability
Age in the registry: 18 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Kessler Foundation Coordinator of this site? Confirm its status | East Hanover | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.