NCT06191549Recruiting
Brain Stimulation Enhance Post-stroke Walking Survivors and Healthy Adults
Effect of Brain Stimulation on Locomotor Skill Acquisition in Stroke
Source: ClinicalTrials.gov · Last updated 14 Oct 2026
Brief summary (registry, in English)
Recent studies showed that a non-invasive, low-intensity brain stimulation called transcranial direct current stimulation (tDCS) can effectively increase motor neuron excitability in the brain and therefore promotes functional recovery after stroke. Thus, the overall purpose of this research project is to examine the effect of brain stimulation on motor skill learning in stroke survivors.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 70 (estimated)
- First submitted
- 20 Dec 2023
- Start date
- 1 May 2025
- Primary completion date
- 31 Aug 2027
- Lead sponsor
- The University of Texas Medical Branch, Galveston
- Diseases
- Stroke
- NCT number
- NCT06191549
What you commit to
- Study type: Interventional
- Planned participants: 70
- From 1 May 2025 to the primary completion date, 31 Aug 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Have any metal implants, cardiac pacemakers, or history of seizures
- Ongoing orthopedic or other neuromuscular disorders that will restrict exercise training
- Any vestibular dysfunction or unstable angina
Other
- Pregnant women
- MRI or CT evidence of involvement of the basal ganglia or cerebellum, evidence of multiple lesions, or evidence of any other brain damage or tumors
- Significant cognitive deficits (inability to follow a 2-step command) or severe receptive or global aphasia
Who the study is looking for
- Age between 21 and 90 years
- Medical history of a unilateral stroke occurring ≥ 6 months prior to enrollment
- MRI or CT evidence from the imaging report shown that the stroke involves the corticospinal tract
- Hemiparesis involving the lower extremity (Fugl-Meyer Lower Extremity Motor Test)
- No passive range of motion limitation in bilateral hips and knees
- Limitation of ankle passive range of motion to 10 degrees of dorsiflexion or less
- Visual acuity can be corrected by glasses or contact lens to 20/20
- Able to walk independently with/without assistant devices for 10 meters
- Able to maintain standing position without any assistance \>= 30 sec (Short Physical Performance Battery)
- Evaluation of cognitive status: Mini-mental status examination (MMSE) score ≥ 24
Age in the registry: 21 years to 90 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Texas Medical Branch Coordinator of this site? Confirm its status | Galveston | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.