NCT06192602Active, not recruiting
Effects of an Acceptance-based Medication Adherence Therapy for Recent-onset Psychosis
Testing the Effectiveness of an Acceptance-based Adherence Therapy for People With Recent-onset Psychosis: A Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 19 Mar 2026
Brief summary (registry, in English)
This randomized controlled trial aimed to examine the effectiveness of a 10-session acceptance-based, insight-inducing medication adherence therapy (AIM-AT) program for recent-onset psychosis (in addition to usual care) over a 12-month follow-up (i.e., at immediate, 6-month, and 12-month post-intervention).
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 126 (actual)
- First submitted
- 21 Dec 2023
- Start date
- 1 Feb 2023
- Primary completion date
- 28 Feb 2026
- Lead sponsor
- Chinese University of Hong Kong
- Diseases
- Schizophrenia
- NCT number
- NCT06192602
What you commit to
- Study type: Interventional
- Participants enrolled: 126
- From 1 Feb 2023 to the primary completion date, 28 Feb 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Participated in/have recently been receiving other psychotherapies;
Other illness
- Having comorbidity of another mental illness (learning disability, cognitive or personality disorder) and/or clinically significant medical disease; and
Other
- Having communication and/or visual/hearing difficulty.
Who the study is looking for
- primarily diagnosed with psychosis (termed recent-onset), including brief, first-episode and other psychotic disorders according to the criteria of the DSM-V (American Psychiatric Association, 2013);
- had the mental illness ≤5 years (defined as recent-onset psychosis in recent literature)
- Hong Kong Chinese residents, aged 18-64 years;
- Global Assessment of Functioning scores ≥51, indicating mild to moderate symptoms and difficulties in psychosocial/occupational functioning (American Psychiatric Association, 2013), thus being mentally stable to comprehend AIM\_AT and/or psychoeducation training;
- Unsatisfactory medication adherence as indicated by the Adherence Rating Scale of \<2 (Hayward et al.,1995) during screening; and
- Able to read/understand Cantonese/Mandarin.
Age in the registry: 18 years to 64 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Integrated Community Centers for Mental Wellness Coordinator of this site? Confirm its status | Hong Kong | Hong Kong SAR China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.