NCT06197321Completed
Non-invasive Prediction of Fluid and Noradrenaline Responsiveness Using the Carotid Wave Intensity.
Non-invasive Prediction of Fluid and Noradrenaline Responsiveness in Critical Care Patients Using the Carotid Wave Intensity (cWI)
Source: ClinicalTrials.gov · Last updated 18 Feb 2025
Brief summary (registry, in English)
The goal of this observational study is to study a new method to compute ventricular-arterial coupling (VAC) in adult intensive care patients after cardiac surgery. VAC is a metric that describes the interaction between the heart and the arterial system. The new method of measuring VAC uses carotid ultrasound measurements. The main questions this study aims to answer are: * Can VAC measured using carotid ultrasound predict the hemodynamic response to drugs? * What is the concordance of VAC measurements obtained via carotid ultrasound with VAC measurements obtained via the standard, single-beat method? Measurements will be performed in the operating room and at the ICU.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 120 (actual)
- First submitted
- 5 Dec 2023
- Start date
- 15 Jan 2024
- Primary completion date
- 30 Nov 2024
- Lead sponsor
- Catharina Ziekenhuis Eindhoven
- Diseases
- Coronary artery disease
- NCT number
- NCT06197321
What you commit to
- Study type: Observational
- Participants enrolled: 120
- From 15 Jan 2024 to the primary completion date, 30 Nov 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Emergency surgery
Other illness
- Patient with chronic obstructive pulmonary disease (COPD) gold stage 3 or 4
- Moderate to severe aortic valve disease
- History of cerebrovascular accident or transient ischemic attack
- History of cerebral trauma
Other
- No informed consent for study participation
- Within the first 3 hours of ICU admission noradrenaline infusion is not increased or started, and/or a fluid bolus is not given; both on indication of the attending physician
- Pregnancy
- Atrial fibrillation
- Carotid artery stenosis \>50%
- Morbid obesity (BMI \>40 kg/m2)
Who the study is looking for
- Adult patients (≥18 years)
- Admitted to the ICU after cardiac surgery
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Catharina Ziekenhuis Coordinator of this site? Confirm its status | Eindhoven | Netherlands | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.