NCT06206629Completed
Contralateral R1 in Amyotrophic Lateral Sclerosis
Evaluation of Contralateral R1 Component of the Blink Reflex in Patients With Amyotrophic Lateral Sclerosis
Source: ClinicalTrials.gov · Last updated 9 Oct 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting both upper and lower motor neurons. Electroneuromyography is an important tool for the diagnosis. Previous studies have shown that different components of the blink reflex, such as the latencies of homo- and contralateral R2 responses can be affected. Studies have found that a contralateral R1 component can appear in neurological diseases with affection of the central nervous system especially upper motor neuron, such as HTLV1 infection. Thus, you aim to determine if a contralateral R1 component could be present in ALS.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 120 (actual)
- First submitted
- 4 Jan 2024
- Start date
- 15 Feb 2024
- Primary completion date
- 5 Sept 2024
- Lead sponsor
- Hospices Civils de Lyon
- Diseases
- ALS (motor neurone disease)
- NCT number
- NCT06206629
What you commit to
- Study type: Observational
- Participants enrolled: 120
- From 15 Feb 2024 to the primary completion date, 5 Sept 2024
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous damage linked to another cause of the cranial nerves
- Prior brainstem lesions
Other
- Persons deprived of liberty by a judicial or administrative decision
- Patient under judicial protection, unable to express consent
Who the study is looking for
- For patients
- Aged 18 to 99 years old
- Referred for suspected motor neuromuscular disease
- Collection of non-opposition
- For healthy subjects:
- Aged 18 to 99 years old
- Absence of any neurological pathology
- Collection of non-opposition
Age in the registry: 18 years to 99 years · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hôpital Neurologique Pierre Wertheimer Coordinator of this site? Confirm its status | Bron | France | Unknown status |
| CHU de Nantes Coordinator of this site? Confirm its status | Nantes | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.