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NCT06212128Completed

RAPIDO vs LCRT vs Upfront Surgery - a Prospective Cohort Study

Novel Objective Comparison of Short-term Surgical Outcomes From Total Mesorectal Excision Between Total Neoadjuvant Therapy - Rapido Protocol, Standard Long Course Radiotherapy and Upfront Surgery

Source: ClinicalTrials.gov · Last updated 30 Apr 2026

Brief summary (registry, in English)

Aim: We evaluated the surgical outcomes of 3 groups of patients with rectal cancers - RAPIDO vs standard long course radiotherapy (LCRT) vs upfront surgery to objectively determine the effects of TNT on TME. Methods: A review of prospectively collected data was performed for patients who have rectal cancer and underwent low anterior resection from January 2016 to May 2022. Data on patient demographics, disease staging, peri-operative details and up to 2-year follow-up outcomes were analysed. The surgical and oncological outcomes were compared. Patients were followed up until 31 May 2022.

Status (registry)
Completed
Study type
Observational
Enrollment
57 (actual)
First submitted
27 Dec 2023
Start date
1 Jan 2016
Primary completion date
31 May 2022
Lead sponsor
Sengkang General Hospital
NCT number
NCT06212128

What you commit to

  • Study type: Observational
  • Participants enrolled: 57
  • From 1 Jan 2016 to the primary completion date, 31 May 2022
  • No sites listed in no country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • emergency surgery

Other illness

  • unresectable metastatic disease at presentation

Who the study is looking for

  • diagnosed with rectal cancer
  • due to undergo ultra-low anterior resection (ULAR)

Age in the registry: 21 years to 99 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

This page is information, not medical advice. Discuss any trial with your doctor.