NCT06212791Recruiting
EXercise Cardiac Magnetic Resonance Assessment of Left Atrial Mechanics Following Ablation
EXCLAMATORY: EXercise Cardiac Magnetic Resonance Assessment of Left Atrial Mechanics Following Ablation TO Reduce Atrial Fibrillation Burden and Correlation With Exercise CapacitY Longitudinal Study
Source: ClinicalTrials.gov · Last updated 12 Mar 2026
Brief summary (registry, in English)
Longitudinal, observational cohort study to evaluate changes in left atrial (LA) reservoir function during exercise and overall exertional capacity in patients following catheter ablation for paroxysmal atrial fibrillation (AF).
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 50 (estimated)
- First submitted
- 19 Dec 2023
- Start date
- 26 Dec 2024
- Primary completion date
- Mar 2028
- Lead sponsor
- Virginia Commonwealth University
- Diseases
- Atrial fibrillation
- NCT number
- NCT06212791
What you commit to
- Study type: Observational
- Planned participants: 50
- From 26 Dec 2024 to the primary completion date, Mar 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior ablation (catheter based or surgical) for AF
- Prior cardiac surgery
Other illness
- Chronic kidney disease with estimated glomerular filtration rate \<30 mL/min/1.73m2
- Unrelated cardiomyopathy that is expected to limit exercise capacity, including but not limited to:
- Hypertrophic cardiomyopathy
- Cardiac amyloidosis
- Constrictive pericarditis
- Pulmonary arterial hypertension
Other
- Persistent or permanent AF
- Significant sinus node dysfunction
- Implanted pacemaker or defibrillator
- Contraindication to or inability to complete cardiovascular magnetic resonance study
- Contraindication to or inability to complete exercise testing
- Severe left ventricular hypertrophy
- Active pregnancy
Who the study is looking for
- Age ≥18 years
- Diagnosis of paroxysmal AF
- Left ventricular ejection fraction ≥50%
- Scheduled for catheter ablation
- Able to speak, hear, and read English
- Willing and able to provide informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Virginia Commonwealth University Coordinator of this site? Confirm its status | Richmond | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.