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NCT06212791Recruiting

EXercise Cardiac Magnetic Resonance Assessment of Left Atrial Mechanics Following Ablation

EXCLAMATORY: EXercise Cardiac Magnetic Resonance Assessment of Left Atrial Mechanics Following Ablation TO Reduce Atrial Fibrillation Burden and Correlation With Exercise CapacitY Longitudinal Study

Source: ClinicalTrials.gov · Last updated 12 Mar 2026

Brief summary (registry, in English)

Longitudinal, observational cohort study to evaluate changes in left atrial (LA) reservoir function during exercise and overall exertional capacity in patients following catheter ablation for paroxysmal atrial fibrillation (AF).

Status (registry)
Recruiting
Study type
Observational
Enrollment
50 (estimated)
First submitted
19 Dec 2023
Start date
26 Dec 2024
Primary completion date
Mar 2028
Lead sponsor
Virginia Commonwealth University
NCT number
NCT06212791

What you commit to

  • Study type: Observational
  • Planned participants: 50
  • From 26 Dec 2024 to the primary completion date, Mar 2028
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Prior ablation (catheter based or surgical) for AF
  • Prior cardiac surgery

Other illness

  • Chronic kidney disease with estimated glomerular filtration rate \<30 mL/min/1.73m2
  • Unrelated cardiomyopathy that is expected to limit exercise capacity, including but not limited to:
    • Hypertrophic cardiomyopathy
    • Cardiac amyloidosis
    • Constrictive pericarditis
  • Pulmonary arterial hypertension

Other

  • Persistent or permanent AF
  • Significant sinus node dysfunction
  • Implanted pacemaker or defibrillator
  • Contraindication to or inability to complete cardiovascular magnetic resonance study
  • Contraindication to or inability to complete exercise testing
  • Severe left ventricular hypertrophy
  • Active pregnancy

Who the study is looking for

  • Age ≥18 years
  • Diagnosis of paroxysmal AF
  • Left ventricular ejection fraction ≥50%
  • Scheduled for catheter ablation
  • Able to speak, hear, and read English
  • Willing and able to provide informed consent

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
Virginia Commonwealth University
Coordinator of this site? Confirm its status
RichmondUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.