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NCT06213272Recruiting

Combined Exercise and Targeted Therapy for Post-Stroke Reading Deficits

Improving Reading Competence in Aphasia With Combined Aerobic Exercise and Phono-Motor Treatment

Source: ClinicalTrials.gov · Last updated 13 Aug 2026

Brief summary (registry, in English)

The goal of the proposed project is to test the effectiveness of a novel hybrid approach to treatment of reading disorders after stroke, in which exercise training will be used in combination with a targeted reading treatment. This approach is expected to increase cerebral circulation and help to rebuild and strengthen the damaged phonological neural networks. Through this combinatory approach, the study aims to enhance the reading and language improvements seen with existing treatments.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
70 (estimated)
First submitted
26 Dec 2023
Start date
18 Apr 2024
Primary completion date
1 Mar 2029
Lead sponsor
Kessler Foundation
Diseases
Stroke
NCT number
NCT06213272

What you commit to

  • Study type: Interventional
  • Planned participants: 70
  • From 18 Apr 2024 to the primary completion date, 1 Mar 2029
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • prior neurological disease
  • concurrent speech and language therapy

Other

  • contraindication to MRI
  • developmental learning or reading disability (i.e., developmental dyslexia)
  • contraindication to exercise

Who the study is looking for

  • fluent and literate in English prior to stroke
  • 1st ever stroke
  • more than 3 months post-stroke
  • post-stroke reading deficits, defined as reading aloud accuracy \<83% for single words or \<65% for readable nonwords
  • living within a 50-mile radius from Kessler Foundation.

Age in the registry: 18 years to 85 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Kessler Foundation
Coordinator of this site? Confirm its status
West OrangeUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.