NCT06213480Completed
Next-Generation Synbiotic in Individuals With Overweight or Obesity
Supplementation With a Next-Generation Synbiotic in Individuals With Overweight or Obesity: A Triple-Blinded Randomized Controlled Clinical Trial
Source: ClinicalTrials.gov · Last updated 2 Oct 2026
Brief summary (registry, in English)
This study plans to evaluate the effect of consuming a symbiotic (probiotic + prebiotic) for 3 months on body weight, body composition, glucose sensitivity, and psychological parameters, as well as on gut and blood microbial composition. Synbiotic consumption is preceded by a 3-day antibiotic course to help ensure the opening of new niches (houses) for the upcoming beneficial bacteria.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 75 (actual)
- First submitted
- 20 Dec 2023
- Start date
- 2 Feb 2024
- Primary completion date
- 20 May 2025
- Lead sponsor
- Texas Christian University
- Diseases
- Obesity
- NCT number
- NCT06213480
What you commit to
- Study type: Interventional
- Participants enrolled: 75
- From 2 Feb 2024 to the primary completion date, 20 May 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- currently taking metformin, GLP-1 agonists, insulin, or fiber
- have taken antiacids, laxatives, probiotics, or medication that affects your immune system in the past month
- are currently participating in a weight loss intervention (dietetic or medication)
- have had any bariatric surgery
Other illness
- have a history of inflammatory bowel disease, colon cancer, or chronic polyps
- have been diagnosed with type 1 or type 2 diabetes
- have active cancer
- have had a history of recent (within 30 days) diarrhea illness
- have a known allergy to any component of the study product
- have had an acute inflammatory infection or inflammatory condition in the past 4 weeks
Other
- are following a vegetarian, vegan, carnivore, or keto diet
- pregnant, planning pregnancy during the study period, or lactating
- have used antibiotics, antifungals, or antivirals in the past 3 months
- have had \>10% weight variation in the past 6 months
Who the study is looking for
- be between 18-50 years of age
- have a BMI between 25.0-40.0
Age in the registry: 18 years to 50 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Texas Christian University, Rickel Building Coordinator of this site? Confirm its status | Fort Worth | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.