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NCT06214611Completed

Prospective Validation of Adaptive Radiotherapy (ART) in Patients With Head and Neck Tumors

Adaptive Radiotherapy in the Treatment of Patients With a Histologically Confirmed Malignant Tumor in the Head and Neck Region: Prospective Validation of ART in Patients With HNT (Prospektive Validierung Der ART Bei Patientinnen Und Patienen Mit Kopf-Hals Tumoren,)

Source: ClinicalTrials.gov · Last updated 20 Oct 2026

Brief summary (registry, in English)

Adaptive radiotherapy (ART) includes image-guided radiotherapy (IGRT) and also offers further possibilities for plan adaptation. A particularly high benefit can be expected for patients in whom the clinical target volume (CTV) can show a significant change in shape from fraction to fraction due to anatomical deviations. The shape and position constancy of the CTV during the course of the series is examined in this trial. Dosimetric disadvantages of this type have not been reported so far. The aim of this study is to identify patients who benefit from ART at an early stage and to select them for this method, and then to continue to offer ART to this patient group. If a relevant reduction in the minimum planning target volume (PTV) margins with ART compared to IGRT is demonstrated in this study, patients could be treated with ART.

Status (registry)
Completed
Study type
Interventional
Enrollment
30 (actual)
First submitted
28 Dec 2023
Start date
15 Nov 2023
Primary completion date
15 Dec 2025
Lead sponsor
University Hospital, Essen
NCT number
NCT06214611

What you commit to

  • Study type: Interventional
  • Participants enrolled: 30
  • From 15 Nov 2023 to the primary completion date, 15 Dec 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • 1\. Pregnancy

Who the study is looking for

  • ECOG 0-1
  • Histopathology confirmation
  • Compliance
  • Tumor in the head and neck region
  • Indication for radiotherapy

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Department for Radiotherapy, University Hospital Essen, National Center for Tumor Diseases (NCT) West
Coordinator of this site? Confirm its status
EssenGermanyUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.