NCT06215248Recruiting
Myocardial Dysfunction Evaluation in Lower Extremity Arterial Disease Patients With Deformation Analysis
Assessment of Dysfunction in Left Cardiac Chambers With Strain-analyses in Patients With Lower Extremity Arterial Disease
Source: ClinicalTrials.gov · Last updated 16 Dec 2025
Brief summary (registry, in English)
Single centre observational study to assess lower extremity arterial disease (LEAD) patients' cardiac dysfunction with strain analyses and to assess connections between cardiac dysfunction, metabolomic changes and target organ damage in LEAD.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 162 (estimated)
- First submitted
- 10 Jan 2024
- Start date
- 1 Feb 2024
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- Tartu University Hospital
- Diseases
- Heart failure
- NCT number
- NCT06215248
What you commit to
- Study type: Observational
- Planned participants: 162
- From 1 Feb 2024 to the primary completion date, 31 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Known heart failure in history
- Any acute or chronic autoimmune or rheumatic disease
- Cardiac structural disease in history: inflammatory, infiltrative diseases, nonischemic cardiomyopathies
- Acute coronary syndrome in last 3 months
- Moderate to severe cardiac valvular disease
- Cardiac valvular disease operative/invasive treatment in history
- Cardiac implantable electronic device (CIED)
- Transitory ischemic attack or stroke in last 3 months
- Untreated hypertension (noninvasive blood pressure measurement ≥180/110 mmHg during recruitment)
- Malignant tumor with radiation treatment to thorax, oncologic or biologic treatment in history
- Chronic hematologic disease (except for anemia)
- Acute or chronic infectious disease
Lab values
- Chronic severe kidney dysfunction (eGFR \<30 ml/min/1,73 m²)
- Anemia with hemoglobin \<80 g/L
Age
- Age \<35 or \>85 years
- Malignant tumor with \<5 years of remission
Other
- BMI ≥40 kg/m²
- Severe COPD (GOLD C or D)
- Moderate to severe asthma (according to GINA 2022 criteria)
- Severe liver dysfunction
Who the study is looking for
- Fontaine I-IV class symptoms
- Confirmed diagnosis of LEAD
- Age 35-85
- Has to have at least of the following: hypertension, diabetes, coronary artery disease or the patient smokes
Age in the registry: 35 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Tartu University Hospital Coordinator of this site? Confirm its status | Tartu | Estonia | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.