NCT06215937Completed
Quantitative Sensory Testing and Central Sensitization in Endometriosis
Source: ClinicalTrials.gov · Last updated 2 Sept 2026
Brief summary (registry, in English)
Endometriosis is a gynecologic condition where there is growth of endometrial-like tissue outside the uterus, leading to severe pelvic pain. Despite conventional treatment, many patients experience persistent pelvic pain due to central sensitization (CS), where the central nervous system amplifies pain signals. Quantitative Sensory Testing (QST) enables objective testing of CS. However, there are several patient-reported questionnaires that have shown promising potential as subjective proxies of CS. Therefore, in this study, our objective is to validate six patient-reported questionnaires as measures of CS by comparing them to each other and determining whether each questionnaire correlates with QST thresholds.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 126 (actual)
- First submitted
- 11 Jan 2024
- Start date
- 1 May 2024
- Primary completion date
- 28 Feb 2026
- Lead sponsor
- BC Women's Hospital & Health Centre
- Diseases
- Endometriosis
- NCT number
- NCT06215937
What you commit to
- Study type: Observational
- Participants enrolled: 126
- From 1 May 2024 to the primary completion date, 28 Feb 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous laparotomy (i.e. large abdominal incision)
- Physical trauma (ex., surgery, scaring) to heterotropic QST test site(s) (i.e. deltoid muscle in the shoulder, thenar eminence).
Other illness
- Diabetes or neurological disease predisposing to neuropathic pain.
Other
- Currently pregnant or breastfeeding.
- Post-menopausal.
- Does not speak English - Patients who do not speak English will be excluded to maintain the safety and well-being of the patient, as not understanding the test and process may harm the patient and reduce the validity of the results. We do not have research funding for a translator. Additionally, patients who require a translator are not typically included in the data registry and therefore are unlikely to be in our sample.
- QST specific criteria
Who the study is looking for
- New or re-referral appointment at the BC Women's Centre for Pelvic Pain and Endometriosis.
- Consented to be contacted for future research in the centre data registry (EPPIC NCT02911090; H16-00264).
- Surgically confirmed endometriosis, current imaging diagnosis, or current clinically suspected endometriosis diagnosed at the new or re-referral appointment as coded in the registry.
- 19 to 49 years old.
- Willing and committed to completing six questionnaires about pain.
- QST specific criteria
- Willing and committed to QST testing.
Age in the registry: 19 years to 49 years · Sex: Female
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| BC Women's Hospital & Health Centre Coordinator of this site? Confirm its status | Vancouver | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.