NCT06216496Recruiting
Evaluation of Amino Acid Metabolism Changes in Ovarian Cancer
Evaluation of Amino Acid Metabolism Changes in Participants With Ovarian Cancer by Dynamic Test
Source: ClinicalTrials.gov · Last updated 20 May 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Ovarian cancer is associated with undernutrition in more than half of all cases. The current management of undernutrition-cachexia in cancer is not specific. It is well recognized that the nutritional support currently offered to cancer patients is not effective in combating cachexia, which progresses inexorably, leading to the patient's death. It is therefore necessary to offer specific and adapted care, in particular by optimizing the quality of nitrogen intake. To achieve this, the investigators first need to define the specific amino acid requirements of cancer patients.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 23 (estimated)
- First submitted
- 26 Dec 2023
- Start date
- 11 Mar 2024
- Primary completion date
- Apr 2026
- Lead sponsor
- University Hospital, Grenoble
- Diseases
- Ovarian cancer
- NCT number
- NCT06216496
What you commit to
- Study type: Interventional
- Planned participants: 23
- From 11 Mar 2024 to the primary completion date, Apr 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Subject receiving more than 4,500 euros in compensation for participation in other research involving the human body in the 12 months preceding this study.
Other illness
- Significant active comorbidity requiring long-term drug treatment (e.g. organ failure, diabetes) or history of pathology likely to impact amino acid metabolism (e.g. urea or homocysteine cycle abnormalities, tyrosinemia, alkaptonuria, hyperprolinemia, organic aciduria).
- Significant biological abnormalities (not explained by the underlying pathology for women with ovarian cancer)
Other
- vegetarian or vegan diet
- difficult venous access
- Persons covered by articles L1121-5 to L1121-8 of the CSP (corresponding to all protected persons: pregnant women, parturients, nursing mothers, persons deprived of their liberty by judicial or administrative decision, persons subject to a legal protection measure).
- Liver metastases
Who the study is looking for
- Histological diagnosis of high-grade serous ovarian cancer not immediately resectable (stage III or IVa) managed at Grenoble Alpes University Hospital.
- Affiliation to the French social security system.
- Able to understand and follow the instructions necessary for the conduct of the trial, and having given written consent for the study.
Age in the registry: 40 years to 70 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Chu Grenoble Alpes Coordinator of this site? Confirm its status | La Tronche | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.