NCT06219694Recruiting
Laser Acupuncture for Chronic Migraine
Enhancing Chronic Migraine Preventive Therapy: Laser Acupuncture as an Add-On Treatment for Patients With Unsatisfactory Pharmacological Effect, a Pilot Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 20 Nov 2025
Brief summary (registry, in English)
A single-blind randomized controlled trial was conducted from October 2024 to May 2025. Chronic migraine patients were randomly assigned in a 1:1 ratio to receive either Laser acupuncture or sham treatment. The co-primary outcomes were changes in monthly migraine days (MMD) and acute headache medications usage days per month from baseline, and Hospital Anxiety and Depression Scale (HADS), and Beck's Depression Inventory(BDI) evaluation. Evaluations were taken at baseline and each follow-up point. After \>6 months follow up as washing out time, the sham group received complementary laser acupuncture treatment and follow up for another 3 months, compared the Headache related parameters (onset, duration, pain scale, current medication for headache, menstrual cycle).
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 3 Jan 2024
- Start date
- Jan 2022
- Primary completion date
- May 2022
- Lead sponsor
- Taichung Veterans General Hospital
- Diseases
- Migraine
- NCT number
- NCT06219694
What you commit to
- Study type: Interventional
- Planned participants: 60
- From Jan 2022 to the primary completion date, May 2022
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- patients who had received another LA therapy or traditional acupuncture at baseline
Other illness
- cognitive or psychological impairment interfering with the participant's ability to receive LA protocol and describe symptoms
Age
- migraine onset after the age of 50
Other
- patients with missing data at baseline or during the follow-up period.
Who the study is looking for
- patients aged above 20 years old and had CM managed pharmacologically, including preventive and/or acute migraine medications, and in addition, those who had refused preventive agent despite recommendation of the neurologist;
- patients who had unsatisfactory effect of current pharmacological treatments, defined as they self-reported
- patients who had a minimum of one-year history of migraine with or without aura.
Age in the registry: 20 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Taichung Veterans General Hospital Coordinator of this site? Confirm its status | Taichung | Taiwan | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.