NCT06220409Completed
Gut Microbiota Composition, Cognitive Function, and Physical Fitness in Multiple Sclerosis Patients
Effect of Dance Classes on Gut Microbiota Composition, Cognitive Function, and Physical Fitness in Multiple Sclerosis Patients
Source: ClinicalTrials.gov · Last updated 24 Jan 2024
Brief summary (registry, in English)
The evidence suggests that multiple sclerosis (MS) induces a decline in motor and cognitive function and provokes a shift in gut microbiome composition in patients. Therefore, the purpose of this study is to explore the effect of a 12-week dance class training program on the gut microbiota composition, motor function, and cognitive function of patients with MS. The investigators will also study the following: * The impact of organised physical activity on quality of life * The impact of organised physical activity on body composition and metabolic parameters (e.g., insulin sensitivity, lipid profile, ect.) * The impact of organised physical activity on physical fitness (e.g., VO2max, Power, ect.)
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 29 (actual)
- First submitted
- 9 Jan 2024
- Start date
- 1 Mar 2022
- Primary completion date
- 30 Aug 2023
- Lead sponsor
- Comenius University
- Diseases
- Multiple sclerosis
- NCT number
- NCT06220409
What you commit to
- Study type: Interventional
- Participants enrolled: 29
- From 1 Mar 2022 to the primary completion date, 30 Aug 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Simultaneous participation in an interventional study or participation in an interventional study in the last two months before study inclusion
Other illness
- serious comorbidities including psychiatric diseases
- Significant cognitive impairment, clinically relevant or progressive disease (e.g., liver, kidney, cardiovascular system, respiratory tract, vascular system, brain, metabolism, thyroid) that could affect the course of the study
- Clinically relevant addiction or substance abuse disorder (defined as alcohol, drug and drug abuse)
- Malignant disease
- Insufficient mental possibility of cooperation Eating disorder
Other
- Nicotine consumption of \> 5 cigarettes per day and no willingness to stop consumption during therapeutic fasting.
Who the study is looking for
- patients with multiple sclerosis, diagnosed according to official diagnostic criteria according to McDonald 2010
- Consent ability and written consent
- The expanded disability status scale (EDSS) \<5.5
- age 30 - 50
Age in the registry: 30 years to 50 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Biological and Medical Science, Faculty of Physical Education and Sport, Comenius University Coordinator of this site? Confirm its status | Bratislava | Slovakia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.