NCT06220747Completed
Effectiveness of HPV Vaccine Among Adolescents and Reproductive Women
Effectiveness of Single Dose or Two Doses of HPV Vaccine Among Adolescents and Reproductive Women: A Test-negative Control Study
Source: ClinicalTrials.gov · Last updated 8 Oct 2026
Brief summary (registry, in English)
To assess the effectiveness of HPV vaccine 2 doses or less to prevent HPV high risk infection among adolescents and adults. We conduct the test-negative control study including 12-45 women who interest to do a check-up pap smear. Cases were women who met the inclusion criteria and tested positive for HPV DNA, and controls were defined as women who met inclusion criteria but tested negative. For the proposed HPV VE study, we will enroll nine controls for each enrolled case. The participants will be interviewed about their demographics and vaccine histories. Potential confounders data will be collected by interview or self- report questionnaire. HPV DNA test will be done by urine or self-cervical sampling (optional). In case the participant has previous HPV test result within 1 year, the result will be recorded and analysed without repeating the test.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 760 (actual)
- First submitted
- 15 Jan 2024
- Start date
- Mar 2024
- Primary completion date
- Oct 2024
- Lead sponsor
- Mahidol University
- NCT number
- NCT06220747
What you commit to
- Study type: Observational
- Participants enrolled: 760
- From Mar 2024 to the primary completion date, Oct 2024
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Participant who received 3 doses HPV vaccine.
Other illness
- Participant with history of total hysterectomy and loop electrosurgical excision procedure.
- Any condition that might confound the interpretation of vaccine effectiveness by investigator
Who the study is looking for
- Women aged 12-45 who willing to do HPV test check-up.
- Subject has provided written informed consent prior to performance of any study-specific procedures and is willing and has means to be contacted and to contact the investigator during the study.
- Based on clinical judgment, the participant with underlying chronic disease who has stable and well-controlled medical conditions.
Age in the registry: 12 years to 45 years · Sex: Female · Accepts healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Vaccine Trial Centre, Faculty of Tropical Medicine, Mahidol University, 420/6 Ratchawithi Road, Ratchathewi, Coordinator of this site? Confirm its status | Bangkok | Thailand | Unknown status |
| Vaccine Trial Centre, Faculty of Tropical Medicine, Mahidol University Coordinator of this site? Confirm its status | Bangkok | Thailand | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.