NCT06229873Completed
Smartphone App-guided Inspiratory Muscle Strength Training for Lowering Systolic Blood Pressure
Source: ClinicalTrials.gov · Last updated 19 May 2026
Brief summary (registry, in English)
This clinical trial aims to assess the efficacy of inspiratory muscle strength training (IMST) guided by a smartphone app vs. IMST delivered in a clinical research setting for lowering systolic blood pressure in adults 18 years and older with elevated blood pressure. Participants will perform IMST for 5 minutes a day, 6 days a week, for 6 weeks.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 33 (actual)
- First submitted
- 16 Jan 2024
- Start date
- 27 Jun 2024
- Primary completion date
- 31 Dec 2025
- Lead sponsor
- University of Colorado, Boulder
- Diseases
- High blood pressure
- NCT number
- NCT06229873
What you commit to
- Study type: Interventional
- Participants enrolled: 33
- From 27 Jun 2024 to the primary completion date, 31 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Report of blood donation within 8 weeks prior to enrolling in the study or unwillingness to abstain from donating blood for 8 weeks after completing the study
- Participant report of recent abdominal surgery (past 3 months) or current abdominal hernia
Other illness
- Participant report of a chronic overt medical condition (e.g., unstable cardiovascular disease, recent myocardial infarction or stroke, cancer) that may make it unsafe to participate in the study under the discretion of the study Medical Director.
- Participant report of current ruptured eardrum or any other current condition of the ear
Age
- Age \<18 years
Other
- Inability to abstain from consumption of alcohol for 12 hours on experimental days.
- Participant report of current asthma with very low symptom perception, frequent and severe exacerbations, or abnormally low perception of dyspnea
- Participant report of past or current costochondritis (inflammation of the cartilage that joins the ribs to the breastbone)
Who the study is looking for
- Age 18+ years
- Ability to provide informed consent
- Willing to accept random assignment to condition
- Systolic blood pressure 120-160 mmHg
- Owns an Apple or Android smartphone
- Body mass index \<40 kg/m2
- Subject report of being weight stable in the prior 3 months (\<2 kg weight change) and willing to remain weight stable during the 6-week intervention period
- Subjects taking antihypertensive medications will be included provided they meet the other inclusion criteria, including systolic blood pressure. Medication regimen (prescription and dosing) must be stable for at least 3 months prior to enrollment in the study and must remain stable during the 6-week intervention period. These medications will not be withheld prior to experimental protocols.
- If woman of childbearing age:
- Not pregnant (defined as self-report of pregnancy)
- Willing to be abstinent or use approved contraception (i.e., hormonal contraception, intrauterine devices, barrier methods such as condoms with spermicide, and surgical sterilization) throughout the duration of the study
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Colorado Boulder Coordinator of this site? Confirm its status | Boulder | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.