NCT06234852Completed
Gradual Withdrawal of Low-dose Glucocorticoid in Clinically Quiescent Systemic Lupus Erythematosus.
The Effect of Gradual Withdrawal Versus Maintenance of Low-dose Glucocorticoid in Clinically Quiescent Systemic Lupus Erythematosus, a Pilot Randomized Placebo Controlled Trial.
Source: ClinicalTrials.gov · Last updated 19 Apr 2024
Brief summary (registry, in English)
This study aims compare the flare rate of maintenance versus gradual withdrawal of 5 mg/day prednisone in systemic lupus erythematosus (SLE) patients with clinically quiescent disease.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 20 (actual)
- First submitted
- 14 Jan 2024
- Start date
- 24 Jan 2023
- Primary completion date
- 26 Dec 2023
- Lead sponsor
- Phramongkutklao College of Medicine and Hospital
- Diseases
- Lupus (SLE)
- NCT number
- NCT06234852
What you commit to
- Study type: Interventional
- Participants enrolled: 20
- From 24 Jan 2023 to the primary completion date, 26 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Overlap with other autoimmune disease, except secondary SjS and APS
- Co-morbid with any other condition which required prednisolone treatment
- Documented adrenal insufficiency
Other
- Pregnant or pregnancy planning
- Unable to follow the schedules
Who the study is looking for
- Aged; 20 years
- Diagnosis of SLE according to Systemic Lupus International Collaborating Clinic (SLICC) classification SLE criteria, 2012.
- Achieved clinically quiescent SLE defined as cSLEDAI-2K = 0 for at least 6 months.
- Current treatment regimen including prednisolone 5mg/day. Prednisolone, antimalarials and/or immunosuppressive therapy had to be stable for at least 4 weeks before randomization.
Age in the registry: 20 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Rheumatic Disease Unit, Department of Internal Medicine, Phramongkutklao Hospital and College of Medicine Coordinator of this site? Confirm its status | Bangkok | Thailand | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.