NCT06237127Recruiting
Effects of Goji vs. Fiber on Macular Degeneration
Effects of Goji Berry Intake on Risk of Age-related Macular Degeneration: A Randomized Clinical Trial
Source: ClinicalTrials.gov · Last updated 17 Jul 2026
Brief summary (registry, in English)
The goal of this project is to conduct a clinical trial in 60 participants ranging from age 65-95 who are at risk for age-related macular degeneration (AMD). The study will evaluate the effects of 14g of goji berry intake or an equivalent amount and type of fiber, five days a week for six months, on visual health, gut microbiome profiles, skin carotenoid measures, and lipoprotein profiles.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 19 Jan 2024
- Start date
- 29 Apr 2024
- Primary completion date
- 30 Jun 2027
- Lead sponsor
- University of California, Davis
- Diseases
- Macular degeneration
- NCT number
- NCT06237127
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 29 Apr 2024 to the primary completion date, 30 Jun 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Taking any new medications started within the past 6 months, or changes in medication regimen planned in the next 6 months (stable use greater than 6 months is not exclusionary)
Other illness
- Dislike of, or allergy to, goji berries or any of the ingredients in the fiber-rich wafers and gummies (wheat, corn, oats, soy, natural orange flavor, xylitol, annatto, pectin, or other food ingredients)
- Diagnosed with inflammatory bowel disease, irritable bowel syndrome, other gastrointestinal disorder, undergoing cancer therapy or immunocompromised, or diagnosis of another condition where lutein, zeaxanthin and/or fiber supplementation would be contraindicated or would interfere with ability to participate in the study
- Any physical characteristic or condition that precludes ability to perform study procedures
- Medical or psychiatric condition that, in the opinion of the Investigator, would compromise study findings or prevent the participant from completing the study
Other
- Consumption of \> 2 alcoholic drinks per day
- Indications of substance or alcohol abuse
- Current or planned use of a blood thinner (e.g., Coumadin, Warfarin) at any time during study
- Use of multi-vitamin or any other supplements that contain lutein and/or zeaxanthin (if willing to stop the supplement, subject can be enrolled 6 months from stop date)
- Any planned international travel during the study
- Consuming \>3 servings/day of a combination of spinach, kale, lettuce, orange bell peppers, corn, parsley, squash, broccoli, pumpkin, edamame
- Regularly consuming \>3 eggs/day
- Currently participating in any other interventional research study
Who the study is looking for
- Family history of AMD
- Hyperlipidemia or managed diabetes
- 65 - 95 years of age
Age in the registry: 65 years to 95 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| UC Davis Eye Center, Tschannen Eye Institute Coordinator of this site? Confirm its status | Sacramento | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.