NCT06237179RecruitingPhase 1/2
Behavioral Exercise Training to Reduce Cardiovascular Disease Risk
Behavioral Exercise Training to Reduce Cardiovascular Disease Risk in Men Undergoing Androgen Deprivation Therapy (EXTRA-PC)
Source: ClinicalTrials.gov · Last updated 2 Mar 2026
Brief summary (registry, in English)
To test the preliminary effectiveness of a home-based exercise training (ET) intervention to improve exercise capacity (VO2 peak \& 6-minute walk distance \[6MWD\]) among prostate cancer (PC) patients compared to controls receiving healthy living education (HLE) at 12 weeks.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 1/2
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 4 Jan 2024
- Start date
- 21 Feb 2024
- Primary completion date
- 31 Jan 2028
- Lead sponsor
- Virginia Commonwealth University
- Diseases
- Prostate cancer
- NCT number
- NCT06237179
What you commit to
- Study type: Interventional · Phase 1/2
- Planned participants: 60
- From 21 Feb 2024 to the primary completion date, 31 Jan 2028
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Have pre-existing overt cardiovascular disease/heart failure;
- Active illness/infection;
Lab values
- Hemoglobin \< 7.0 grams/dL
- Platelet count \< 10 x 109/L
Other
- Be unable to undergo MRI (i.e., ferromagnetic materials in body, inability to lie flat, claustrophobia);
- Have contraindications to exercise testing;
Who the study is looking for
- Be diagnosed with stage II/III/IV prostate cancer
- Be currently undergoing treatment with ADT (intermittent or prolonged)
- Have completed local curative-intent treatment, including prostatectomy or definitive radiation;
- Be \>40 years of age up to 85;
- Be willing to sign an informed consent with HIPAA authorization form;
- Not have any hearing or sight impairments that result in the inability to use the telephone or hear normal conversation;
- Must be able to join an intervention group by personal computer, smartphone or telephone call and should agree to recording of an interview;
- Be without any serious medical condition that precludes safe participation in an exercise program;
- Speak English
Age in the registry: 40 years to 85 years · Sex: Male · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Virginia Commonwealth University/Massey Cancer Center Coordinator of this site? Confirm its status | Richmond | United States | Recruiting |
| Richmond Veterans Affairs Medical Center Coordinator of this site? Confirm its status | Richmond | United States | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.