NCT06237673Completed
The "CAD-Man" EXTEND Study
A Randomized, Controlled Trial in Patients With Suspected Coronary Artery Disease Based on Acute or Chronic Atypical Angina Pectoris - EXTEND
Source: ClinicalTrials.gov · Last updated 20 Mar 2026
Brief summary (registry, in English)
CAD-Man Extend is the long-term follow-up (clinical, laboratory, and computed tomography (CT) imaging) of a single-center, randomized, controlled CAD-Man trial comparing a CT-first strategy with a direct- invasive coronary angiography (ICA) diagnostic and management strategy, in 329 patients clinically referred for ICA with atypical angina or chest pain. Overall goal: The extension of CAD-Man follow-up (clinical, laboratory, and CT imaging) to approximately 10 years will provide the opportunity to compare plaque burden with CT-guided management versus direct-ICA at long-term and other endpoints.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 318 (actual)
- First submitted
- 20 Dec 2023
- Start date
- 1 Dec 2023
- Primary completion date
- 11 Jan 2025
- Lead sponsor
- Charite University, Berlin, Germany
- Diseases
- Coronary artery disease
- NCT number
- NCT06237673
What you commit to
- Study type: Interventional
- Participants enrolled: 318
- From 1 Dec 2023 to the primary completion date, 11 Jan 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Any health condition that would cause concern that participation would not be in the best interest of health (eg, extensive comorbidities)
Other
- Pregnancy
Who the study is looking for
- Patients with suspected CAD
- Patients with atypical angina
- Patients who have previously participated in the CAD-Man study and have not died at a median follow-up of 3.3 years.
Age in the registry: 30 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Charité Universitätsmedizin Berlin Coordinator of this site? Confirm its status | Berlin | Germany | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.