NCT06240299Recruiting
Neurofeedback for Nociplastic Pain in Rheumatoid Arthritis (NECTAR)
Neurofeedback for Nociplastic Pain in Rheumatoid Arthritis
Source: ClinicalTrials.gov · Last updated 15 Jun 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Rheumatoid arthritis is an autoimmune condition, causing inflammation and pain. Yet pain may persist even when inflammation has been treated. This residual pain, called nociplastic pain, has symptoms of a chronic pain condition called fibromyalgia. There are few effective therapies to address this residual pain. Published literature shows that fibromyalgia can be treated by neurofeedback, a noninvasive method that is based on the voluntary modulation of cortical activity. In this pilot study, the investigators want to test the effect of neurofeedback on the fibromyalgia component of pain in rheumatoid arthritis, and also to investigate its effects on related symptoms such as fatigue and sleep disturbance.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 16 (estimated)
- First submitted
- 6 Dec 2023
- Start date
- 24 Jun 2024
- Primary completion date
- 29 Jan 2027
- Lead sponsor
- NHS Greater Glasgow and Clyde
- Diseases
- Rheumatoid arthritis
- NCT number
- NCT06240299
What you commit to
- Study type: Interventional
- Planned participants: 16
- From 24 Jun 2024 to the primary completion date, 29 Jan 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Under active management of pain team (changing medications, other non pharmacological pain treatment)
Other illness
- Major confounding neurological diseases including Multiple Sclerosis, Stroke, Traumatic Brain Injury, Parkinson's Disease, and Alzheimer's Disease)
- Medical or psychiatric conditions that in the judgment of study personnel would preclude participation in the study (psychosis, suicidal ideation etc)
Other
- Unable to understand the task.
- Unable to provide a written informed consent.
- Unable to understand English.
- Involved in other interventional experimental studies
Who the study is looking for
- Fulfilment of the ACR/EULAR Classification Criteria for rheumatoid arthritis (RA)
- Fulfilment of the American College of Rheumatology criteria for chronic widespread pain
- Stable disease (swollen joint count ≤1 and CRP ≤10)
- Has normal or corrected to normal vision and hearing abilities
- Right-handed (to reduce baseline motor response test heterogeneity)
- Pain intensity equal or larger than 4 on the Visual Numerical Scale (0 no pain, 10, max pain imaginable)
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Clinical Research Facility (CRF), Queen Elizabeth University Hospital Coordinator of this site? Confirm its status | Glasgow | United Kingdom | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.