NCT06243731Recruiting
A Study of Maribavir in Adults With Kidney Failure Who Have a Cytomegalovirus (CMV) Infection After Transplantation
Retrospective Chart Review of Safety Outcomes Associated With Use of Maribavir in Patients With Post-transplant Refractory Cytomegalovirus (CMV) Infection and Comorbid Severe Chronic Kidney Disease (CKD) or Comorbid End-stage Renal Disease (ESRD), Including Patients on Peritoneal Dialysis or Hemodialysis
Source: ClinicalTrials.gov · Last updated 16 Dec 2025
Brief summary (registry, in English)
The main aim of this study is to assess the safety of maribavir in adults with severe CKD or comorbid ESRD including participants on artificial filtering of the kidney (dialysis) or the blood (hemodialysis). In this study, already existing data will be collected from the participant's medical records. The study will only review data collected as part of the normal clinical routine and will not impact the standard medical care and treatment of participants.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 10 (estimated)
- First submitted
- 29 Jan 2024
- Start date
- 3 Nov 2025
- Primary completion date
- 31 Jan 2027
- Lead sponsor
- Takeda
- Diseases
- Chronic kidney disease
- NCT number
- NCT06243731
What you commit to
- Study type: Observational
- Planned participants: 10
- From 3 Nov 2025 to the primary completion date, 31 Jan 2027
- 25 sites in 7 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- There are no exclusion criteria for this study.
Who the study is looking for
- Adults more than and equal to (≥) 18 years of age at index date.
- Diagnosis of comorbid ESRD or comorbid severe CKD prior to the index date.
- If ESRD (including participants on peritoneal dialysis or hemodialysis): participant diagnosed with ESRD confirmed by an estimated glomerular filtration rate (eGFR) less than (\<) 15 milliliters per minute per 1.73 square meters (mL/min/1.73m\^2).
- If severe CKD: participant diagnosed with severe CKD confirmed by an eGFR of 15 to \<30 mL/min/1.73m\^2 at index.
- Participant has undergone solid organ transplant (SOT) or hematopoietic stem cell transplantation (HSCT) before index date.
- Participant was diagnosed with refractory (with or without resistance) CMV during the latest post-transplant period.
- Participant initiated treatment with maribavir in routine practice within the eligibility period and received at least 1 dose of maribavir.
- Informed consent provided (where required by local regulations) before data collection commences.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (25)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hopital Erasme - PPDS Coordinator of this site? Confirm its status | Anderlecht | Belgium | Not yet recruiting |
| UZ Leuven - PPDS Coordinator of this site? Confirm its status | Leuven | Belgium | Not yet recruiting |
| Universitatsklinikum Leipzig Coordinator of this site? Confirm its status | Leipzig | Germany | Not yet recruiting |
| Universitätsklinikum Würzburg Coordinator of this site? Confirm its status | Würzburg | Germany | Not yet recruiting |
| North Estonia Medical Centre Foundation Coordinator of this site? Confirm its status | Tallinn | Estonia | Recruiting |
| Tartu University Hospital Coordinator of this site? Confirm its status | Tartu | Estonia | Recruiting |
| Hospital Universitario Cruces Coordinator of this site? Confirm its status | Barakaldo | Spain | Not yet recruiting |
| Hospital Clinic de Barcelona Coordinator of this site? Confirm its status | Barcelona | Spain | Not yet recruiting |
| Hospital Universitario Vall d'Hebron - PPDS Coordinator of this site? Confirm its status | Barcelona | Spain | Recruiting |
| C.H. Regional Reina Sofia - PPDS Coordinator of this site? Confirm its status | Córdoba | Spain | Not yet recruiting |
| Hospital Universitario de Bellvitge Coordinator of this site? Confirm its status | L'Hospitalet de Llobregat | Spain | Not yet recruiting |
| Hospital Universitario Ramón y Cajal Coordinator of this site? Confirm its status | Madrid | Spain | Not yet recruiting |
| Hospital Regional Universitario de Malaga - Hospital General Coordinator of this site? Confirm its status | Málaga | Spain | Recruiting |
| Hospital Universitario Virgen del Rocio - PPDS Coordinator of this site? Confirm its status | Seville | Spain | Not yet recruiting |
| CHU de Bordeaux - Hôpital Pellegrin Coordinator of this site? Confirm its status | Bordeaux | France | Recruiting |
| CHU de Brest - Hopital La Cavale Blanche Coordinator of this site? Confirm its status | Brest | France | Recruiting |
| AP-HP Hopital Henri Mondor Coordinator of this site? Confirm its status | Créteil | France | Recruiting |
| Chu de Grenoble Alpes - Hopital Michallon Coordinator of this site? Confirm its status | La Tronche | France | Recruiting |
| CHU de Montpellier - Hôpital Lapeyronie Coordinator of this site? Confirm its status | Montpellier | France | Recruiting |
| Queen Elizabeth Hospital Birmingham Coordinator of this site? Confirm its status | Birmingham | United Kingdom | Not yet recruiting |
| Dorset County Hospital Coordinator of this site? Confirm its status | Dorchester | United Kingdom | Not yet recruiting |
| King's College Hospital Coordinator of this site? Confirm its status | London | United Kingdom | Not yet recruiting |
| Wrexham Maelor Hospital Coordinator of this site? Confirm its status | Wrexham | United Kingdom | Not yet recruiting |
| Azienda Ospedaliera Dei Colli Ospedale Monaldi Coordinator of this site? Confirm its status | Naples | Italy | Not yet recruiting |
| Fondazione IRCCS Policlinico San Matteo Coordinator of this site? Confirm its status | Pavia | Italy | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.