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NCT06244953Recruiting

Timely Interventions to Enable and Reach Patients With Heart Failure, and Their Caregivers With Palliative Care

Source: ClinicalTrials.gov · Last updated 16 Jul 2026

Brief summary (registry, in English)

There is evidence for the effectiveness and feasibility of the individual components of TIER-HF-PC, however there is a need to test how these individual components interact to allow the researchers to deliver TIER-HF-PC as a model of care in its totality. In the short term, this study will assess if TIER-HF-PC is beneficial for patients and caregivers.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
240 (estimated)
First submitted
17 Jan 2024
Start date
14 Aug 2024
Primary completion date
31 Oct 2026
Lead sponsor
National Cancer Centre, Singapore
NCT number
NCT06244953

What you commit to

  • Study type: Interventional
  • Planned participants: 240
  • From 14 Aug 2024 to the primary completion date, 31 Oct 2026
  • 4 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Patients:
    • have cognitive impairment (e.g., dementia)
    • have severe, untreated, active mental illness (e.g., major depressive disorder)
    • have ventricular assist device implant.
    • have non-reversible hearing or visual loss or
    • are active drug abuser or
    • already known to a palliative care service.
  • Caregivers who meet any of the exclusion criteria at baseline will be ineligible for the study:
    • have cognitive impairment (e.g., dementia) or
    • have severe, untreated, active mental illness (e.g., major depressive disorder)
    • have non-reversible hearing or visual loss.
    • are active drug abuser or
    • are a domestic helper for the patient

Who the study is looking for

  • Patients:
    • 21 years or older and
    • able to communicate in English/Chinese/Malay and
    • be of stage C or D heart failure, as defined by American College of Cardiology/American Heart Association (ACC/AHA) classification system and
    • have functional limitation of New York Heart Association (NYHA) functional status of at least 2 or more and
    • be deemed by their cardiologist's clinical judgement to have an expected prognosis of at least 6 months survival, and
    • have had a heart failure related hospitalization event (e.g. symptomatic decompensated heart failure) within 6 months prior to recruitment and
    • have a phone that allows telecommunication.
  • Caregivers must meet all the following inclusion criteria to be eligible for the study :
    • direct, unpaid, family caregiver of the patient;
    • self-reported by the patient to be the main person to be either:
    • responsible for up to 4 hours a day of caregiving tasks
    • and/or decision maker/spokesperson with the medical team
    • Caregiver may or may not live in the same residence as the patient.
    • Caregivers must be 21 years and above.
    • Able to communicate in English/Chinese/Malay.

Age in the registry: 21 years to 99 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (4)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Khoo Teck Puat Hospital
Coordinator of this site? Confirm its status
SingaporeSingaporeRecruiting
National Heart Centre Singapore
Coordinator of this site? Confirm its status
SingaporeSingaporeRecruiting
National Cancer Centre Singapore
Coordinator of this site? Confirm its status
SingaporeSingaporeRecruiting
Sengkang General Hospital
Coordinator of this site? Confirm its status
SingaporeSingaporeRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.