NCT06245512Recruiting
Diagnostic and Prognostic Markers of Endometriosis in Menstrual Blood
RECHERCHE DE MARQUEURS DIAGNOSTIQUES ET PRONOSTIQUES DE L'ENDOMETRIOSE DANS LE SANG DES REGLES CHEZ LES FEMMES EN AGE DE PROCREER
Source: ClinicalTrials.gov · Last updated 16 Apr 2026
Brief summary (registry, in English)
The goal of this observational study is to identify diagnostic and prognostic biomarkers for endometriosis using menstrual blood, an easily accessible yet overlooked biological fluid in women of reproductive age, affected or not by endometriosis The main questions it aims to answer are: * are there relevant differences in the menstrual blood of women affected by endometriosis compared to women without endometriosis? * do some of these differences disappear or lessen when the disease is treated by surgery? Participants will answer questions relevant to endometriosis and provide menstrual blood 1 to 3 times (self-collected with a menstrual cup). A subgroup of participants affected by endometriosis that will undergo surgery for their regular care will provide menstrual blood before and after their surgery. Researchers will compare the menstrual blood of women with and without endometriosis, and before and after surgery to see if they can identify significant differences.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 250 (estimated)
- First submitted
- 30 Jan 2024
- Start date
- 31 Jul 2024
- Primary completion date
- 30 Mar 2027
- Lead sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
- Diseases
- Endometriosis
- NCT number
- NCT06245512
What you commit to
- Study type: Observational
- Planned participants: 250
- From 31 Jul 2024 to the primary completion date, 30 Mar 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- endometriosis surgery within the last 3 months.
Other illness
- Autoimmune diseases
- Chronic diseases other than endometriosis (diabetes, hypertension)
- Infectious diseases (HIV, HBV, if known)
- History of menstrual toxic shock syndrome
- For patients with endometriosis:
Other
- For all participants:
- A person who is the subject of a judicial safeguard measure (by declaration)
Who the study is looking for
- For all participants:
- Women 18-45 of age who
- Have their period
- Have given their written consent
- Have already used a menstrual cup as a method of hygienic protection
- Residing or working in Ile de France (Paris Metropolitan area, France)
- For participants with endometriosis:
- diagnosis of endometriosis established by surgery or imaging (ultrasound and/or MRI)
- presence of one or more painful symptoms \> 3 on a visual scale (dysmenorrhea and/or dyspareunia and/or chronic pelvic pain) and/or infertility
- for the surgery subgroup: planned surgery in the next 3 months
- For participants without endometriosis:
- painful symptoms \< or equal to 3 on a visual scale (for dysmenorrhea and dyspareunia and chronic pelvic pain),
- absence of intense period pain in adolescence (leading to taking pills to control this pain and/or peri-menstrual school absenteeism)
Age in the registry: 18 years to 45 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hôpital Cochin Coordinator of this site? Confirm its status | Paris | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.