NCT06255041Completed
Detection of Cancer in Breath Samples by Trained Detection Dogs
A Double-Blind Observational Study to Evaluate the Ability of Trained Detection Dogs to Detect Cancer in Breath Samples: The Rainbow Study
Source: ClinicalTrials.gov · Last updated 15 May 2026
Brief summary (registry, in English)
The goal of this study is to show that trained detection dogs can identify breast, lung, prostate or colorectal cancer by sniffing masks containing breath samples. In this study, individuals who will undergo cancer screening at an integrated cancer prevention center or biopsy for a suspected malignancy, will be asked to provide a breath sample by breathing into a surgical mask. The mask will then be sent to the laboratory, where trained detection dogs will determine if the person who provided the mask has breast, lung, prostate or colorectal cancer or if the person does not have these types of cancer. The results provided by the dogs will be compared to the actual cancer screening results or biopsy results in order to determine the accuracy of cancer detection by the trained dogs.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 1386 (actual)
- First submitted
- 4 Feb 2024
- Start date
- 10 Feb 2021
- Primary completion date
- 31 Jan 2024
- Lead sponsor
- SpotitEarly
- Diseases
- Prostate cancer, Lung cancer, Colorectal cancer
- NCT number
- NCT06255041
What you commit to
- Study type: Observational
- Participants enrolled: 1386
- From 10 Feb 2021 to the primary completion date, 31 Jan 2024
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Undergoing chemotherapy for any purpose.
- Had a medical procedure in the chest cavity and/or airways in the two weeks prior to providing the breath sample that may interfere with the ability to correctly provide a breath sample.
Other illness
- Was diagnosed with cancer or was treated for cancer in the seven years preceding the study, excluding non-metastatic skin tumors that were surgically removed.
- Has a Helicobacter pylori infection.
- Has a peptic ulcer disease.
- Has a flare-up of an inflammatory bowel disease (Crohn's disease/ulcerative colitis).
- has an active infection, such as COVID-19, abscess, bacterial/viral/fungal infection, pneumonia, laryngitis, intestinal inflammation, active tuberculosis infection.
Other
- Pregnant or breastfeeding
Who the study is looking for
- Men and women aged 18 and over.
- Signing an informed consent prior to performing the test.
- Intended to undergo screening tests for cancer detection.
- Did not smoke 2 hours before providing the breath sample
- Did not drink coffee in the hour before providing the breath sample
- Did not drink an alcoholic beverage in the hour prior to providing the breath sample.
- Did not eat food in the hour before providing the breath sample.
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Rambam Health Care Campus Coordinator of this site? Confirm its status | Haifa | Israel | Unknown status |
| Tel-Aviv Sourasky Medical Center Coordinator of this site? Confirm its status | Tel Aviv | Israel | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.