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NCT06265155Completed

Triggers of Acute Ischemic Stroke Due to Large Vessel Occlusion

Triggers of Acute Ischemic Stroke Due to Large Vessel Occlusion: A Case-crossover Study

Source: ClinicalTrials.gov · Last updated 23 Jun 2026

Brief summary (registry, in English)

Acute ischemic stroke has a high incidence, ischemic stroke caused by large vessel occlusion is serious and has a poor prognosis, and its triggers in the short term before onset are not clear. The aim of this study was to evaluate the short-term risk of acute ischemic stroke caused by multiple triggers. In this trial, through a case-crossover study design, patients were asked about the exposure to each trigger in the previous year and the exposure during the preictal risk period (the exposure observed during the risk period) for each potential trigger of acute ischemic stroke caused by large vessel occlusion. To evaluate the relative risk of ischemic stroke resulting from exposure to triggers, comparing exposure during the dangerous period with the usual frequency of exposure. Relative risks and corresponding 95% CIs were estimated for past-year exposure and past-year mean exposure (assessed as chronic risk factors) and time to last exposure (assessed as triggers). Scientifically evaluate exposure to a range of potential triggers, including infection, mood, smoking, alcohol consumption, diarrhea and vomiting, extreme temperature changes, and several factors that increase blood pressure and their risk of developing acute ischemic stroke.

Status (registry)
Completed
Study type
Observational
Enrollment
302 (actual)
First submitted
30 Jan 2024
Start date
1 Feb 2024
Primary completion date
30 Jun 2025
Lead sponsor
Anzhi Li
Diseases
Stroke
NCT number
NCT06265155

What you commit to

  • Study type: Observational
  • Participants enrolled: 302
  • From 1 Feb 2024 to the primary completion date, 30 Jun 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • severe bleeding or known significant bleeding tendency
  • presence of other conditions that the investigator considers inappropriate for enrollment

Other

  • severe organ dysfunction
  • life expectancy of less than 90 days

Who the study is looking for

  • age ≥ 18 years
  • imaging diagnosis of large vessel occlusion
  • CT excluded intracranial hemorrhage
  • signed informed consent form by the patient himself or his legal representative

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
Suzhou Hospital Anhui Medical University
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SuzhouChinaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.