NCT06266403Recruiting
Evaluating Verbal Communication in Structured Interactions: Theoretical and Clinical Implications
Source: ClinicalTrials.gov · Last updated 7 Aug 2026
Brief summary (registry, in English)
The goal of this clinical trial is to learn about the effect of communicative interaction on verbal communication in people with amyotrophic lateral sclerosis (ALS) and age-matched speakers. The question is, What are the effects of communicative interaction on verbal communication in people with ALS? Participants will read words and sentences while they are in a solo setting and interactive setting.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 300 (estimated)
- First submitted
- 29 Jan 2024
- Start date
- 5 Nov 2024
- Primary completion date
- 28 Feb 2029
- Lead sponsor
- Penn State University
- Diseases
- ALS (motor neurone disease)
- NCT number
- NCT06266403
What you commit to
- Study type: Interventional
- Planned participants: 300
- From 5 Nov 2024 to the primary completion date, 28 Feb 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- None - if volunteer meets the inclusion criteria, then they will be enrolled
Who the study is looking for
- Speakers with amyotrophic lateral sclerosis (ALS) (PALS-people with ALS)
- diagnosis of ALS following the revised EL Escorial criteria
- no history of other neurological conditions (e.g., stroke)
- no cognitive impairment assessed by Telephone Montreal Cognitive Assessment (mini MoCA)
- detectable speech disturbance according to the ALS Functional Rating Scale-Revised (ALSFRS-R)
- the ability to produce single words
- being a native speaker of American English (AE).
- Age-matched Speakers
- passing the remote hearing screening
- having no known speech, language, or neurological disorders per self-report
- no cognitive impairment assessed by Telephone Montreal Cognitive Assessment (mini MoCA)
- being a functionally native monolingual speaker of American English.
- Unfamiliar Interlocutors
- passing the remote hearing screening
- having no known speech, language or neurological disorders per self-report
- being a native monolingual speaker of American English
- having no experience communicating with people with dysarthria
- being between the ages of 18 and 40.
Age in the registry: 18 years to 90 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Speech Core, Pennsylvania State University Coordinator of this site? Confirm its status | University Park | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.