NCT06268743Completed
Effects of a Combined Exercise Intervention on the Gut Microbiome of People With Type 2 Diabetes
Understanding the GUT Microbiome Through a Fitness Intervention of Aerobic and Resistance Training for Individuals With Type 2 Diabetes Mellitus (GUTFIT Study)
Source: ClinicalTrials.gov · Last updated 5 May 2026
Brief summary (registry, in English)
The goal of this experimental trial is to learn about the changes in bacterial diversity in individuals with type 2 diabetes who perform endurance and strength training at different intensities. Participants with type 2 diabetes will be randomly assigned to 16 weeks of either moderate-intensity endurance and strength training or high-intensity endurance and strength training. Researchers will compare the moderate-intensity and high-intensity exercise groups for differences in glycemia and bacterial diversity.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 40 (actual)
- First submitted
- 12 Feb 2024
- Start date
- 29 Feb 2024
- Primary completion date
- 7 Apr 2026
- Lead sponsor
- University of New Brunswick
- Diseases
- Type 2 diabetes
- NCT number
- NCT06268743
What you commit to
- Study type: Interventional
- Participants enrolled: 40
- From 29 Feb 2024 to the primary completion date, 7 Apr 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Not diagnosed with type 2 diabetes;
- A self-reported diagnosis of low iron concentrations, anemia, or being treated for these conditions;
- A diagnosis of any red blood cell altering condition (i.e., sickle cell anemia, poikilocytosis);
- Currently living with any cardiovascular disease which would impact the ability to participate in exercise safely;
- Currently prescribed any medication which would impact the ability to use a heart rate monitor to accurately track intensity.
Other
- Partaking in a self-reported regular exercise regimen, defined as consistent participation in running or jogging activity, attending exercise classes every week, or averaging 10,000 steps per day or more over seven days;
- Currently performing two days of resistance training per week;
- Having an injury that would prevent safe participation in the intervention;
Who the study is looking for
- Adults aged 19 - 64 years old;
- Diagnosed with type 2 diabetes;
- An HbA1c \>= 7.0%;
- Not currently meeting the recommended levels of physical activity for optimal health (i.e., 150 minutes of moderate-to-vigorous physical activity and 2+ days/week of resistance training);
- Average less than 10,000 steps per day over the last seven days;
- No change in diabetes medications over the last three months.
Age in the registry: 19 years to 64 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Cardiometabolic Exercise & Lifestyle Laboratory Coordinator of this site? Confirm its status | Fredericton | Canada | Unknown status |
Related publications
This page is information, not medical advice. Discuss any trial with your doctor.