NCT06269874Not yet recruiting
Study Comparing Two Administration Pathways for Adenosine During Microvascular Function Assessment
A Single-centric, ProspectivE, Randomized Controlled Study Comparing Two Administration Pathways for Adenosine During Invasive Assessment of Microvascular Function in Patients With ANOCA.
Source: ClinicalTrials.gov · Last updated 8 Oct 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The aim of this study is to investigate the agreement and reproducibility between intravenous and intracoronary adenosine administration during invasive assessment of microvascular function. Goals of this study are: 1. Agreement and reproducibility between intravenous and intracoronary adenosine administration in the IMR (Index of microvascular resistance) value. 2. Agreement and reproducibility of FFR(fractional flow reserve), CFR (coronary flow reserve), MRR (microvascular resistance reserve), RRR (resistive reserve ratio) and reproducibility of each of these as compared with CFRabs (absolute coronary flow). 3. Time required for IMR measurements
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 13 Feb 2024
- Start date
- 2 Mar 2027
- Primary completion date
- 31 Jul 2027
- Lead sponsor
- Johannes Gutenberg University Mainz
- Diseases
- Coronary artery disease
- NCT number
- NCT06269874
What you commit to
- Study type: Interventional
- Planned participants: 40
- From 2 Mar 2027 to the primary completion date, 31 Jul 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Secondary or tertiary atrioventricular block without prior pacemaker implantation
- Previous CABG (coronary artery bypass graft) with patent grafts to the left anterior descending coronary
Other illness
- Bronchial asthma, COPD (chronic obstructive pulmonary disease)
- Epicardial coronary disease (FFR \<0.80 with evidence of a focal stenosis) in the left anterior descending territory
Age
- Age \<18 years
Other
- Inability to provide informed consent
Who the study is looking for
- Chronic coronary syndrome (including patients with anginal equivalents).
- Indication to cardiac catheterization;
- Indication to the assessment of microvascular function (note: patients will be asked for participation and consented prior to the first measurement of microvascular function, which will be conducted as per clinical indication)
- Willingness to participate and ability to understand, read and sign the informed consent
- Age\>18 years
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Center of Cardiology, Cardiology I, university hospital Mainz Coordinator of this site? Confirm its status | Mainz | Germany | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.