NCT06270238Recruiting
Efficacy of Personalized Repetitive Transcranial Magnetic Stimulation Protocol Based on Functional Reserve to Enhance Upper Limb Function in Subacute Stroke Patients
Efficacy of Personalized Repetitive Transcranial Magnetic Stimulation Protocol Based on Functional Reserve to Enhance Upper Limb Function in Subacute Stroke Patients: A Multi Center, Randomized, Single Blind, Parallel Group Prospective Clinical Trial
Source: ClinicalTrials.gov · Last updated 24 Apr 2026
Brief summary (registry, in English)
The objective of this study was to determine the effects of protocols of repetitive transcranial magnetic stimulation (rTMS) therapy based on the functional reserve of each hemiplegic stroke patient in subacute phase, compared to conventional low-frequency rTMS therapy on contralateral M1. Investigators hypothesized that the functional reserve of each hemiplegic stroke patient will be different, and therefore an appropriate simulating target for rTMS therapy is needed. In addition, this approach could be more effective compared to conventional protocols applied to stroke patients regardless of their severity, predicted mechanism of motor function recovery, or functional reserves.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 120 (estimated)
- First submitted
- 13 Feb 2024
- Start date
- 13 Feb 2024
- Primary completion date
- 30 Sept 2026
- Lead sponsor
- Samsung Medical Center
- Diseases
- Stroke
- NCT number
- NCT06270238
What you commit to
- Study type: Interventional
- Planned participants: 120
- From 13 Feb 2024 to the primary completion date, 30 Sept 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- those with contraindications to rTMS, such as epilepsy, implanted metal objects in the head, or a history of craniotomy,
- those with progressive of hemodynamically unstable medical conditions,
- those with coexisting neurological conditions, such as spinal cord injury or Parkinson's disease,
- those with major psychiatric disorders, such as major depression, schizophrenia, or dementia,
Other
- those having contraindications to conduct an MRI study,
- those who are pregnant or lactating ,
- patients who have refused to participate in this study.
Who the study is looking for
- hemiplegic stroke patients in the subacute phase (7 days to 3 months from the onset) who are currently hospitalized,
- FMA score of the upper extremity ≤42,
- adequate language and cognitive function to perform at least a 1-step obey-command,
- pre-stroke functional level of modified Rankin Scale (mRS) ≤1,
- aged ≥19 years old,
- patients willing to sign the informed consent.
Age in the registry: 19 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Samsung Medical Center Coordinator of this site? Confirm its status | Seoul | South Korea | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.